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Association of inflammation, dyslipidemia, obesity and physical activity status...
Pereira, Patrícia Feliciano; Oliveira, Michelle Dias de; Dias, Roberto Sousa; Paula, Sérgio Oliveira de; Guedes, Juliano MagalhãesThe aim of this study was to verify the association between inflammatory biomarkers, dyslipidemia, obesity and physical activity status in 10-years old children. Ninety-four children participated in this study and were classified into eutrophic (n=36), overweight (n=34) or obese (n=24) according to their body mass index (BMI). The genic expression of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α) and...
Toxicity of bovicin HC5 against mammalian cell lines and the role of cholestero...
Paiva, Aline Dias; Oliveira, Michelle Dias de; Paula, Sérgio Oliveira de; Baracat-Pereira, Maria Cristina; Breukink, Eefjan; Mantovani, Hilário CuquettoBacteriocins are ribosomally synthesized antimicrobial peptides produced by Bacteria and some Archaea. The assessment of the toxic potential of antimicrobial peptides is important in order to apply these peptides on an industrial scale. The aim of the present study was to investigate the in vitro cytotoxic and haemolytic potential of bovicin HC5, as well as to determine whether cholesterol influences bacterioci...