Introduction: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder, characterized by a strong genetic component, heterogeneous phenotypic presentation and complex genetic architecture. [1, 2] Identification of ASD risk genes and biological pathways is key to understand this disorder.[3, 4] Despite the large number of genes associated with ASD, its genetic etiology is still not fully understoo...
The skin mycobiome is a largely unexplored component of the human microbiome, especially in critically ill patients. Fungal colonisation in the Intensive Care Unit (ICU) may be influenced by underlying comorbidities and hospital-related risk factors, potentially impacting patient outcomes. This pilot study aimed to characterize the diversity and abundance of skin fungi in ICU patients during their first week of...
We present an exploratory study comparing human player performance against online and offline AI learning techniques—the Naive Bayes Classifier and Genetic Algorithms, respectively—using a simple turn-based game. Human player performance is also assessed according to gender, age, experience playing games, and boredom level during game sessions. Human players and AI techniques are shown to obtain statistically e...
O plano de estágio teve por base o seguinte: - Introdução ao diagnóstico eletrónico BMW; - Realização de campanhas técnicas da marca; - Realização de ações de manutenção de acordo com o plano de manutenção da marca; - Montagem e calibragem de pneus; - Realização de alinhamentos de veículos conforme a norma; - Preparação de entrega de carros novos; - Preparação de entrega de motas novas; - BMW MOTORRAD: Montagen...
Introduction: Candida auris is an emerging pathogen that represents a worldwide health problem due to its global expansion, multidrug resistance, and difficult laboratory identification. Among the risk factors for colonization/infection by C. auris, a stay in an intensive care unit (ICU) stands out. This prospective multicenter study aimed to monitor the trend of the local epidemiology of Candida spp. and unvei...
The skin mycobiota plays a significant role in infection risk, pathogen transmission, and personalized medicine approaches in intensive care settings. This prospective multicenter study aimed to enhance our understanding of intensive care units’ (ICUs’) Candida colonization dynamics, identify modifiable risk factors, and assess their impact on survival risk. Specimens were taken from 675, 203, and 110 patients ...
A vitivinicultura está historicamente ligada a Portugal e ao Município de Alenquer como atividade agrícola de relevante importância económica e social. Em 2017, foi celebrado um Acordo de Cooperação Internacional entre a Câmara Municipal de Alenquer e a Cidade Croata de Benkovac, cidade situada no condado de Zadar. Integram esta parceria o INIAV Polo de Inovação de Dois Portos, a Universidade de Zagreb, Faculda...
Antimicrobial resistance (AMR) is a silent pandemic that represents an urgent threat to human health. Unfortunately, the antibiotic development pipeline is slow even though AMR has been escalating uncontrollably fast, namely amongst Gram-negative pathogens. Although out of use until recently due to their toxic side effects, polymyxins have been revived as a last-line therapeutic option since all other antibioti...