8 documents found, page 1 of 1
Genomic prediction for additive and dominance effects of censored traits in pigs.
SANTOS, V. S.; MARTINS FILHO, S.; RESENDE, M. D. V. de; AZEVEDO, C. F.; LOPES, P. S.; GUIMARÃES, S. E. F.; SILVA, F. F.Age at the time of slaughter is a commonly used trait in animal breeding programs. Since studying this trait involves incomplete observations (censoring), analysis can be performed using survival models or modified linear models, for example, by sampling censored data from truncated normal distributions. For genomic selection, the greatest genetic gains can be achieved by including non-additive genetic effects ...
Regularized quantile regression for SNP marker estimation of pig growth curves.
BARROSO, L. M. A.; NASCIMENTO, M.; NASCIMENTO, A. C. C.; SILVA, F. F.; SERÃO, N. V. L.; CRUZ, C. D.; RESENDE, M. D. V. de; SILVA, F. L.; AZEVEDO, C. F.Background: Genomic growth curves are generally defined only in terms of population mean; an alternative approach that has not yet been exploited in genomic analyses of growth curves is the Quantile Regression (QR). This methodology allows for the estimation of marker effects at different levels of the variable of interest. We aimed to propose and evaluate a regularized quantile regression for SNP marker effect...
Expressed sequenced tags profiling of resistant and susceptible Gyr x Holstein ...
NASCIMENTO, C. S.; MACHADO, M. A.; GUIMARÃES, S. E. F.; MARTINS, M. F.; PEIXOTO, J. de O.; FURLONG, J.; PRATA, M. C. de A.; VERNEQUE, R. da S.Tick resistance in cattle is mainly found in zebu (Bos indicus) animals, although it is also present in some taurine (B. taurus) breeds. In order to characterize functional genes involved in tick resistance/susceptibility in cattle, two cDNA libraries were generated using skin tissues of selected Holstein x Gyr animals. A total of 2700 high-quality reads from both resistant and susceptible cDNA were assembled i...
Association between G316A growth hormone polymorphism and economic traits in pigs.
FARIA, D. A. de; GUIMARÃES, S. E. F.; LOPES, P. S.; PIRES, A. V.; PAIVA, S. R.; SOLLERO, B. P.; WENCESLAU, A. A.Made available in DSpace on 2018-06-05T00:37:19Z (GMT). No. of bitstreams: 1 ID276201.pdf: 145785 bytes, checksum: 37e3ec1b566d51d1715d74bff6a5bb80 (MD5) Previous issue date: 2006-12-18
Bayesian model combining linkage and linkage disequilibrium analysis for low de...
SILVA, F. F.; JEREZ, E. A. Z.; RESENDE, M. D. V. de; VIANA, J. M. S.; AZEVEDO, C. F.; LOPES, P. S.; NASCIMENTO, M.; LIMA, R. O. de; GUIMARÃES, S. E. F.We combined linkage (LA) and linkage disequilibrium (LDA) analyses (emerging the term ?LALDA?) for genomic selection (GS) purposes. The models were fitted to a simulated dataset and to a real data of feed conversion ratio in pigs. Firstly, the significant QTLs (quantitative trait locus) were identified through LA-based mixed models considering the QTL-genotypes as random effects by means of genotypic identity b...
Factor analysis applied to genome prediction for high-dimensional phenotypes in...
TEIXEIRA, F. R. F.; NASCIMENTO, M.; NASCIMENTO, A. C. C.; SILVA, F. F. e; CRUZ, C. D.; AZEVEDO, C. F.; PAIXÃO, D. M.; BARROSO, L. M. A.; VERARDO, L. L.The aim of the present study was to propose and evaluate the use of factor analysis (FA) in obtaining latent variables (factors) that represent a set of pig traits simultaneously, for use in genome-wide selection (GWS) studies. We used crosses between outbred F2 populations of Brazilian Piau X commercial pigs. Data were obtained on 345 F2 pigs, genotyped for 237 SNPs, with 41 traits. FA allowed us to obtain fou...
Gene expression profile in zebu dairy cows (Bos taurus indicus) with mastitis c...
FONSECA, I.; CARDOSO, F. F.; HIGA, R. H.; GIACHETTO, P. F.; BRANDAO, H. de M.; BRITO, M. A. V. P. e; FERREIRA, M. B. D.; GUIMARÃES, S. E. F.Mastitis is an inflammatory response in the mammary gland caused by an influx of somatic cells, composed mainly of neutrophils, macrophages and lymphocytes. The speed and efficacy of the host?s immune response to the invasive pathogen affects the establishment, persistence and severity of the infection. To characterize the gene expression and response mechanism to infection by Streptococcus agalactiae (S. agala...
Paternity in Brazilian goats through the use of DNA microsatellites.
ARAUJO, A. M. de; GUIMARÃES, S. E. F.; PEREIRA, C. S.; LOPES, P. S.; RODRIGUES, M. T.; MACHADO, T. M. M.A total of 292 animals from three breeds (Alpine and Saanen dairy breeds, and the Brazilian naturalized breed Moxotó) were genotyped, comprising 276 paternity cases. Statistical analyses were carried out by using TFPGA and CERVUS programs. Heterozygosis ranged from 0.542 (ILSTS005) to 0.825 (INRA006), with an average of 0.717 for all loci. Polymorphic information content (PIC) was 0.676 and 0.542, and combined ...