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Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of c...
Santiago,Michelle Dias Santos; Carvalho,Deusvenir de Souza; Gabbai,Alberto Alain; Pinto,Mariana Machado Pereira; Moutran,Andrea Regina CorreaTo compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. Method Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were randomized in groups called amitriptyline and aerobic exercise or amitriptyline alone. The following parameters were evaluated: headache frequency, intensity and d...
Patients with neuromyelitis optica have a more severe disease than patients wit...
Bichuetti,Denis Bernardi; Oliveira,Enedina Maria Lobato de; Souza,Nilton Amorin de; Tintoré,Mar; Gabbai,Alberto AlainAlthough neuromyelitis optica (NMO) is known to be a more severe disease than relapsing-remitting multiple sclerosis (RRMS), few studies comparing both conditions in a single center have been done.Methods:Comparison of our previously published cohort of 41 NMO patients with 177 RRMS patients followed in the same center, from 1994 to 2007.Results:Mean age of onset was 32.6 for NMO and 30.2 for RRMS (p=0.2062) wi...
Latin American algorithm for treatment of relapsing-remitting multiple sclerosi...
Finkelsztejn,Alessandro; Gabbai,Alberto Alain; Fragoso,Yara Dadalti; Carrá,Adriana; Macías-Islas,Miguel Angel; Arcega-Revilla,Raul; García-Bonitto,JuanOBJECTIVE: It is estimated that circa 50,000 individuals have relapsing-remitting multiple sclerosis in Latin America. European and North-American algorithms for the treatment of multiple sclerosis do not foresee our regional difficulties and the access of patients to treatment. METHODS: The Latin American Multiple Sclerosis Forum is an independent and supra-institutional group of experts that has assessed the ...
Migraine and cognition in children: a controlled study
Moutran,Andréa Regina Correa; Villa,Thaís Rodrigues; Diaz,Luciana Aparecida Sobirai; Noffs,Maria Helena da Silva; Pinto,Mariana Machado PereiraOBJECTIVE: Evaluate the cognitive functions of children with migraine and compare them to A control group. METHOD: 30 migraineur children and 30 control group children without migraine, age ranging from 8 to 12 years old, were subjected to a cognitive functions assessment with Wechsler Intelligence Scale for Children (WISCIII). RESULTS: Although both groups had a normal cognitive performance, children with migr...
Amyotrophic lateral sclerosis: considerations on diagnostic criteria
Chieia,Marco A.; Oliveira,Acary S.B.; Silva,Helga C.A.; Gabbai,Alberto AlainAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder, compromising the motor neuron, characterized by progressive muscle weakness, with reserved prognosis. The diagnosis is based on inclusion and exclusion clinical criteria, since there is no specific confirmation test. The objective of this research is to critically examine the main diagnosis instrument - El Escorial revisited, from the World Fe...
Conjugal amyotrophic lateral sclerosis in Brazil
Godeiro-Junior,Clecio; Oliveira,Acary S.B.; Felicio,Andre C.; Chieia,Marco A.; Gabbai,Alberto AlainThe origin of amyotrophic lateral sclerosis (ALS) remains unknown, although it seems to be multifactorial. The role of environmental factors has been frequently investigated and suspicion of its influence can be obtained when clusters of a rare disease are described. OBJECTIVE: To describe conjugal cases of ALS in Brazil. METHOD: We describe 2 couples in which both spouses were affected by ALS. Both couples had...
Neuromyelitis optica: brain abnormalities in a Brazilian cohort
Bichuetti,Denis Bernardi; Rivero,René Leandro Magalhães; Oliveira,Daniel May; Souza,Nilton Amorin de; Abdala,Nitamar; Oliveira,Enedina Maria LobatoNeuromyelitis optica (NMO) is a demyelinating disease consisting of relapsing-remitting optic neuritis and myelitis with a more severe course than Multiple Sclerosis. Recently, it has been shown that almost 50% of patients with NMO can have brain magnetic resonance imaging (MRI) abnormalities. We report on six Brazilian patients with NMO, fulfilling the 1999 Wingerchuck criteria for this disease, with abnormal ...
Demyelinating disease in patients with myasthenia gravis
Bichuetti,Denis Bernardi; Barros,Tatiane Martins de; Oliveira,Enedina Maria Lobato; Annes,Marcelo; Gabbai,Alberto AlainMyasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinatin...
Prevalence of cardiovascular risk factors among elderly Brazilians over eighty ...
Pieri,Alexandre; Spitz,Mariana; Lopes,Tania Oliveira; Barros,Claudia Garcia de; Faulhaber,Marcelo Wood; Gabbai,Alberto Alain; Cendoroglo-Neto,MiguelINTRODUCTION: An ischemic stroke is usually a catastrophic event, mostly in the elderly. Cardiovascular involvement is the leading cause of ischemic stroke in this age population and hence the knowledge about its risk factors is important for the definition of specific policies of prevention. PURPOSE: To evaluate the prevalence of cardiovascular risk factors in patients with age equal to or above 80 in a hospit...
Peroneal nerve palsy due to compartment syndrome after facial plastic surgery
Godeiro-Júnior,Clécio O.; Oliveira,Acary Sousa Bulle; Felício,André Carvalho; Barros,Newton; Gabbai,Alberto AlainA 25-year-old white man, right after bilateral rhytidoplasty, presented with agitation, necessiting use of haloperidol. Some hours after, he developed severe pain in his legs and a diagnosis of neuroleptic malignant syndrome (NMS) was considered. Even with treatment for NMS he still complained of pain. A diagnosis of lower limb compartment syndrome (CS) was done only 12 hours after the initial event, being subm...