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Blood biomarkers associated with inflammation predict poor prognosis in cerebra...

de Sousa, Diana Aguiar; Pereira Santos, M. C.; Serra-Caetano, Ana; Lucas Neto, Lia; Sousa, A. L.; Gabriel, D.; Correia, M.; Gil-Gouveia, Raquel

Background and purpose: Experimental studies suggest inflammation can contribute to blood barrier disruption and brain injury in cerebral venous thrombosis (CVT). We aimed to determine whether blood biomarkers of inflammation were associated with the evolution of brain lesions, persistent venous occlusion or functional outcome in patients with CVT. Methods: Pathophysiology of Venous Infarction-Prediction of Inf...


Expert knowledge-based co-development of scenarios for maritime spatial plannin...

Calado, H.; Pegorelli, C.; Vergílio, M.; Hipólito, Cláudia; Campos, A.; Moniz, F.; Costa, A. C.; Pereira da Silva, C.; Fonseca, C.; Frazão Santos, C.

Scenarios constitute narratives or storylines that reasonably describe how the future is likely to unfold. The usefulness of scenarios in Maritime Spatial Planning (MSP) is now recognised within policy and research, with many institutions urging the development of likely trajectories in the future state of the marine environment and space. However, little progress exists in the actual development and applicatio...


Genetic characterization of the red algae Asparagopsis armata and Asparagopsis ...

Santos, R.; Ferreira, A.; Micael, J.; Gil-Rodríguez, M. C.; Machín, M.; Costa, A. C.; Gabriel, D.; Costa, Filipe O.; Parente, M. I.


A two-component pre-seeded dermal-epidermal scaffold

Monteiro, I. P.; Gabriel, D.; Timko, B. P.; Hashimoto, M.; Karajanagi, S.; Tong, R.; Marques, A. P.; Reis, R. L.; Kohane, D. S.

We have developed a bilayered dermal-epidermal scaffold for application in the treatment of full-thickness skin defects. The dermal component gels in situ and adapts to the lesion shape, delivering human dermal fibroblasts in a matrix of fibrin and cross-linked hyaluronic acid modified with a cell adhesion-promoting peptide. Fibroblasts were able to form a tridimensional matrix due to material features such as ...


Calibration of a simplified model describing an urban waste water treatment pil...

Gabriel, D.; Ferreira, Eugénio C.; Valero, F.; Lafuente, J.


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