7 documents found, page 1 of 1
Impact of SARS-CoV-2 Infection and Vaccination on Migraine Symptoms during the ...
Silva, Lénia; Lopes, Adriana; Pontes, Ana; Gonçalves, Ana; Chiteculo, Arlinda; Soares, Beatriz; Teixeira, Inês; Gonçalves, Maria; Alves, MariaIntroduction: Studies have shown the worsening of migraine associated with the COVID-19 infection and the pandemic more broadly. COVID-19 vaccination has also been associated with symptomatic headache, with high frequency among migraineurs. We aimed to assess the impact of COVID-19 diagnosis and vaccine administration on migraine, during the SARS-CoV-2 pandemic. Methods: An online questionnaire was sent to migr...
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Dias, Mariana Carvalho; Reis, Ricardo Soares dos; Santos, João Vasco; Nunes, Ana Paiva; Ferreira, Patricia; Maia, Bruno; Fragata, Isabel; Reis, JoaoIntroduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular ...
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Dias, Mariana Carvalho; dos Reis, Ricardo Soares; Santos, João Vasco; Nunes, Ana Paiva; Ferreira, Patricia; Maia, Bruno; Fragata, Isabel; Reis, JoaoIntroduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular ...
Female preponderance in genetic generalized epilepsies
Videira, Gonçalo; Gabriel, Denis; Freitas, Joel; Samões, Raquel; Chorão, Rui; Lopes, João; Ramalheira, João; Ramalheira, João E.P.; Lemos, CarolinaIntroduction: Epilepsy is more prevalent in men but Genetic Generalized Epilepsies (GGE) seem to be more common in women. A predominant maternal inheritance has been previously described in GGE. Our objective was to determine sex and inheritance patterns in a GGE population compared to mesial temporal lobe epilepsy with hippocampal sclerosis (MTLEHS). Methods: We performed a prospective observational study incl...
Matrix Metalloproteinase-9 levels are associated with brain lesion and persiste...
de Sousa, Diana Aguiar; Pereira Santos, Maria Conceição; Serra-Caetano, Ana; Lucas Neto, Lia; Sousa, Ana Luísa; Gabriel, Denis; Correia, ManuelBackground: Elucidating mechanisms of brain damage in cerebral venous thrombosis (CVT) would be instrumental to develop targeted therapies and improve prognosis prediction. Matrix metalloproteinase-9 (MMP-9), a gelatinase that degrades major components of the basal lamina, has been associated to blood-brain barrier disruption. We aimed to assess, in patients with CVT, the temporal change in serum concentrations...
Spontaneous systolic blood pressure drop early after mechanical thrombectomy pr...
Carvalho Dias, Mariana; Gabriel, Denis; Saraiva, Marlene; Campos, Daniel; Requena, Manuel; García-Tornel, Álvaro; Muchada, Marian; Boned, SandraIntroduction: Spontaneous blood pressure drop within the first 24 h has been reported following arterial recanalisation in ischaemic stroke patients. We aimed to assess if spontaneous blood pressure drop within the first hour after mechanical thrombectomy is a marker of early neurological recovery. Patients and methods: Retrospective observational single-centre study including ischaemic stroke patients treated ...
Refractory myasthenia gravis: Characteristics of a portuguese cohort
Santos, Ernestina; Bettencourt, Andreia; Duarte, Sara; Gabriel, Denis; Oliveira, Vanessa; da Silva, Ana Martins; Costa, Paulo Pinho; Lopes, CarlosIntroduction: Some myasthenia gravis (MG) patients are refractory to conventional treatments. Methods: To describe the clinical features of refractory MG (RMG) and explore the association with human leukocyte antigen HLA-DRB1 alleles, a cohort study of 114 consecutive MG patients was performed. Patients were classified as RMG based on predefined criteria. Results: Twenty-two patients were found to have RMG (19....