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Stratification of ST-Elevation Myocardial Infarction Patients Based on Soluble ...

Napoleão, P; Cabral, L; Selas, M; Freixo, C; Monteiro, MC; Criado, MB; Costa, M; Enguita, F; Viegas-Crespo, AM; Saldanha, C; Mota Carmo, M

Involvement of soluble CD40 ligand (sCD40L) in thrombosis and inflammation on the context of coronary artery disease is currently being revised. In that perspective, we had studied the association of sCD40L with markers of platelet activation and markers of endothelial and vascular function. On that cohort, a stratification of patients with acute myocardial infarction (AMI) 1 month after percutaneous coronary i...


Changes of Soluble CD40 Ligand in the Progression of Acute Myocardial Infarctio...

Napoleão, P; Monteiro, MC; Cabral, L; Criado, MB; Ramos, C; Selas, M; Viegas-Crespo, AM; Saldanha, C; Mota Carmo, M; Cruz Ferreira, R; Pinheiro, T

Reported in vitro data implicated soluble CD40 ligand (sCD40L) in endothelial dysfunction and angiogenesis. However, whether sCD40L could exert that influence in endothelial dysfunction and angiogenesis after injury in acute myocardial infarction (AMI) patients remains unclear. In the present study, we evaluated the association of sCD40L with markers of platelet activation, endothelial, and vascular function du...


Serial Changes in Oxidized Low-Density Lipoprotein Associated with Culprit Vess...

Napoleão, P; Selas, M; Toste, A; Turkman, A; Andreozzi, V; Viegas-Crespo, AM; Pinheiro, T; Cruz Ferreira, R

The aim of the present study was to investigate variations in oxidized LDL (oxLDL) at the onset of acute myocardial infarction (AMI) and over the recovery period, exploring their relationship with coronary disease severity. A follow-up of 50 AMI patients was evaluated against 25 healthy volunteers (reference group). The AMI patients were evaluated at three time points: at admission before the administration of ...


Effects of ileo-rectal anastomosis on cholesterol metabolism in pigs fed either...

Bento, O; Martins, JM; Lança, MJ; Abreu, MC de; Viegas-Crespo, AM; Freire, JP; Almeida, JA; Riottot, M


Cholesterol-lowering effects of dietary blue lupin (Lupinus angustifolius L.) i...

Martins, JM; Riottot, M; Abreu, M.C.; Viegas-Crespo, AM; Lança, MJ; Almeida, JA; Freire, JB; Bento, O


Variações de Marcadores Inflamatórios no Enfarte Agudo do Miocárdio: um Estudo ...

Napoleão, P; Santos, MC; Selas, M; Viegas-Crespo, AM; Pinheiro, T; Cruz Ferreira, R

Actualmente a inflamação é considerada uma componente importante na aterosclerose, desde o seu início até à ruptura da placa seguida de trombose e da progressiva obstrução do vaso. A ruptura da cápsula fibrótica da placa expõe factores de tecido presentes no seu núcleo necrótico que induzem o processo inflamatório, promovendo a adesão celular e a coagulação e que conduzem à formação do trombo. Por seu turno, vá...


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