5 documents found, page 1 of 1
Wide spectrum of F9 variants in hemophilia B families from the Portuguese popul...
Moreira, Isabel; Diniz, Maria João; Tavares, Alice; Morais, Sara; Freitas, B.; Araújo, F.; Gago, T.; Antunes, EM; Catarino, C.; Campos, M.; Almeida, T.Introduction: Hemophilia B is an X-linked bleeding disorder caused by molecular defects in the Factor IX gene (F9), leading to either deficiency or functional abnormality of Factor IX. Actual data indicate a high heterogeneity of variants in F9. Over 1000 different variants have been reported, including pathogenic single nucleotide variants (SNPs), indels and complex variants. Materials and Methods: 86 index pa...
The mean corpuscular volume flow - prognostic value for inflammatory bowel dise...
Roseira, Joana; Sousa, Helena Tavares; Marreiros, Ana; Queiros, P.; Vaz, A. M.; Gago, T.; Contente, L.; Guerreiro, H.The difficult access to thiopurine metabolites therapeutic drug monitoring led to the search for accessible markers to estimate thiopurine’s efficacy.
SexIDI study - sexual satisfaction in inflammatory bowel disease
Roseira, Joana; Sousa, Helena Tavares; Marreiros, Ana; Estevens, D.; Queiros, P.; Vaz, A. M.; Gago, T.; Contente, L.; Guerreiro, H.Sexual satisfaction is among the concerns of patients with Inflammatory Bowel Disease (IBD) being rarely addressed in the outpatient clinic and Quality of Life (QoL) questionnaires. At a time where patient-reported outcomes (PRO) grow in importance, the impact of the disease on sexual health must be valued.
Today, in the endoscopist hands
Roseira, Joana; Sousa, Helena Tavares; Queirós, P.; Antunes, A. G.; Vaz, A. M.; Gago, T.; Contente, L.; Guerreiro, H.Endoscopic submucosal dissection (ESD) was first described as a non-surgical promise for early gastric epithelial lesions.
Ulcerative colitis: let's talk about extent
Vaz, A.; Eusébio, Marta; Antunes, A.; Queiros, P.; Gago, T.; Belo, T.; Caldeira, Paulo; Guerreiro, H.Ulcerative colitis (UC) is a chronic inflammatory disease in which clinical course varies substantially between patients. The extent of the disease is usually pointed out as one of the factors responsible for this variation. With this study, we pretended to evaluate the differences in natural history and pharmacological therapy prescription between left-sided and extended UC.