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Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo ...

Domingues, Neuza; Gaifem, Joana; Matthiesen, Rune; Saraiva, Diana P.; Bento, Luís; Marques, André R.A.; Soares, Maria I.L.; Sampaio, Julio

Funding Information: supported by FCT through projects UIDB/00313/2020 and UIDP/00313/2020. Funding Information: R. S. group has been funded by national funds, through the FCT—project numbers UIDB/50026/2020 and UIDP/ 50026/2020 and 2020.00185. CEECIND to the FCT. Funding Information: N. D. was a holder of a PhD fellowship from the FCT (Ref. N◦: SFRH/BD/51877/2012). Funding Information: The authors acknowledge ...


L-threonine supplementation during colitis onset delays disease recovery

Gaifem, Joana; Gonçalves, Luís G.; Dinis-Oliveira, Ricardo J.; Cunha, Cristina; Carvalho, Agostinho; Torrado, Egídio; Rodrigues, Fernando

Dietary nutrients have emerged as potential therapeutic adjuncts for inflammatory bowel disease (IBD) given their impact on intestinal homeostasis through the modulation of immune response, gut microbiota composition and epithelial barrier stability. Several nutrients have already been associated with a protective phenotype. Yet, there is a lack of knowledge toward the most promising ones as well as the most ad...


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