4 documents found, page 1 of 1
MicroRNAs Biomarkers for Early Screening of Colorectal Cancer
Santos, Daniela; Gaiteiro, Cristiana; Santos, Marlene; Santos, Lúcio; Dinis-Ribeiro, Mário; Lima, LuísBackground: Colorectal cancer (CRC) is the most incident neoplasia in Portugal [1]. When diagnosed early, the 5-year cancer survival rate increases to 90% [2]. However, the current noninvasive screening method for CRC, Fecal Immunochemical Test (FIT), has low sensitivity and specificity for detecting precancerous lesions [3, 4]. Therefore, it is necessary to develop a new screening method for CRC. MicroRNAs (mi...
MicroRNAs biomarkers for early screening of colorectal cancer
Santos, Daniela; Gaiteiro, Cristiana; Santos, Marlene; Santos, Lúcio; Dinis-Ribeiro, Mário; Lima, LuísColorectal cancer (CRC) is the most incident neoplasia in Portugal. When diagnosed early, the 5-year cancer survival rate increases to 90% [2]. However, the current noninvasive screening method for CRC, Fecal Immunochemical Test (FIT), has low sensitivity and specificity for detecting precancerous lesions. Therefore, it is necessary to develop a new screening method for CRC. MicroRNAs (miRs) play a role in gene...
MicroRNA biomarkers as promising tools for early colorectal cancer screening—a ...
Santos, Daniela A. R.; Gaiteiro, Cristiana; Santos, Marlene; Santos, Lúcio; Dinis-Ribeiro, Mário; Lima, LuísColorectal cancer (CRC) ranks as the third most prevalent cancer worldwide. Early detection of this neoplasia has proven to improve prognosis, resulting in a 90% increase in survival. However, available CRC screening methods have limitations, requiring the development of new tools. MicroRNA biomarkers have emerged as a powerful screening tool, as they are highly expressed in CRC patients and easily detectable i...
Glycan affinity magnetic nanoplatforms for urinary glycobiomarkers discovery in...
Azevedo, Rita; Soares, Janine; Gaiteiro, Cristiana; Peixoto, Andreia; Lima, Luís; Ferreira, Dylan; Relvas-Santos, Marta; Fernandes, ElisabeteBladder Cancer (BC) presents one of the highest recurrence rates amongst solid tumours and constitutes the second deadliest disease of the genitourinary track. Non-invasive identification of patients facing disease recurrence and/or progression remains one of the most critical and challenging aspects in disease management. To contribute to this goal, we demonstrate the potential of glycan-affinity glycoproteomi...