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Anti-HMGCR Immune-Mediated Myopathy: Literature Review Based in a Case Report

Baptista, Bernardo; Galaz Tavares, João; Marto, Natália; Bayão Horta, Alexandra; Roque, Rafael

Statins are amongst the most prescribed drugs worldwide and they are generally safe. A rare but potentially serious adverse effect of statins’ therapy has been described– anti-3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (anti-HMGCR) immune-mediated necrotizing myopathy (IMNM) – that can occur years after the drug has beenstarted. We conducted a literature review after illustratinga typical case of anti-HMG...


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