2 documents found, page 1 of 1
Photodynamic antimicrobial chemotherapy (PACT) using phenothiazine derivatives ...
Barbosa, Artur Felipe Santos; Sangiorgi, Bruno Braga; Galdino, Suely L.; Barral-Netto, Manoel; Pitta, Ivan R.; Pinheiro, Antonio Luiz BarbosaTexto completo: acesso restrito. p. 850–855; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-24T13:52:59Z No. of bitstreams: 1 Artur F. Barbosa.pdf: 86697 bytes, checksum: 4a92282542739db1e21fdff38552ed8d (MD5); Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-10-21T16:07:35Z (GMT) No. of bitstreams: 1 Artur F. Barbosa.pdf: 86697 bytes, checksum: 4a92282542739d...
Inhibition of DNA topoisomerase I activity and induction of apoptosis by thiaza...
Barros, Francisco W.A.; Bezerra, Daniel P.; Ferreira, Paulo M. P.; Cavalcanti, Bruno C.; Silva, Teresinha G.; Pitta, Marina G. R.Thiazacridine derivatives (ATZD) are a novel class of cytotoxic agents that combine an acridine and thiazolidine nucleus. In this study, the cytotoxic action of four ATZD were tested in human colon carcinoma HCT-8 cells: (5Z)-5-acridin-9-ylmethylene-3-(4-methylbenzyl)-thiazolidine-2,4-dione — AC-4; (5ZE)-5-acridin-9- ylmethylene-3-(4-bromo-benzyl)-thiazolidine-2,4-dione — AC-7; (5Z)-5-(acridin-9-ylmethylene)-3-...