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PERSISTENT LEFT SUPERIOR VENA CAVA WITH AGENESIS OF THE RIGHT SUPERIOR VENA CAV...

Velho, Tiago R.; Ferreira, Hugo; Guerra, Nuno; Gallego, Javier; Nobre, Ângelo

Persistant left superior vena cava is a rare systemic venous anomaly that can be associated with agenesis of the right superior vena cava. It is usually assymptomatic and discovered incidentally during surgery or other procedures. The authors present the case of a 72-year-old male submitted to an aortic valve replacement surgery. After sternotomy, persistant left superior vena cava and absence of the right supe...


circRNA-miRNA cross-talk in the transition from paroxysmal to permanent atrial ...

Costa, Marina C.; Cortez-Dias, Nuno; Gabriel, André F.; De Sousa, João; Fiuza, Manuela; Gallego, Javier; Nobre, Ângelo; Pinto, Fausto J.

Background: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in western countries. The factors governing the progression of AF to a permanent chronic condition are still not well characterized. Among epigenetic factors, non-coding RNAs (ncRNAs) such as miRNAs and lncRNAs have been recently described as important players involved in the AF progression. We hypothesize about the existence of addit...


Expanding the functional role of miRNAs in the establishment of permanent atria...

Dias, Nuno Cortez; Costa, Marina C.; Sousa, João de; Fiúza, Manuela; Gallego, Javier; Nobre, Ângelo; Pinto, Fausto J.; Enguita, Francisco J.


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