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MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments

Martins, PM; Navarro, S; Silva, A; Pinto, M; Sárkány, Z; Figueiredo, F; Pereira, PJB; Pinheiro, F; Bednarikova, Z; Burdukiewicz, M; Galzitskaya, OV

Reports on phase separation and amyloid formation for multiple proteins and aggregation-prone peptides are recurrently used to explore the molecular mechanisms associated with several human diseases. The information conveyed by these reports can be used directly in translational investigation, e.g., for the design of better drug screening strategies, or be compiled in databases for benchmarking novel aggregatio...


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