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Ethambutol and meropenem/clavulanate synergy promotes enhanced extracellular an...

Olivença, Francisco; Pires, David; Silveiro, Cátia; Gama, Bianca; Holtreman, Frederico; Anes, Elsa; Catalao, Maria João

Increasing evidence supports the repositioning of beta-lactams for tuberculosis (TB) therapy, but further research on their interaction with conventional anti-TB agents is still warranted. Moreover, the complex cell envelope of Mycobacterium tuberculosis (Mtb) may pose an additional obstacle to beta-lactam diffusion. In this context, we aimed to identify synergies between beta-lactams and anti-TB drugs ethambut...

Date: 2024   |   Origin: Veritati - Repositório Institucional da Universidade Católica Portuguesa
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