22 documents found, page 1 of 3
HLA‐A23/HLA‐A24 serotypes and dementia interaction in the elderly: Association ...
Cardoso, Elsa M.; Gomes, Vânia Lourenço; Esgalhado, André J.; Ferreira, Débora Reste; Oliveira, Nádia; Amaral, Ana Saraiva; Martinho, AntónioMHC class I molecules regulate brain development and plasticity in mice and HLA class I molecules are associated with brain disorders in humans. We investigated the relationship between plasma-derived soluble human HLA class I molecules (sHLA class I), HLA class I serotypes and dementia. A cohort of HLA class I serotyped elderly subjects with no dementia/predementia (NpD, n = 28), or with dementia (D, n = 28) w...
Clinical characteristics and variables associated with COVID-19 morbidity and m...
Arrais, Margarete; Dias, Welwitschia; Silva, Maura; Neto, Luquenia; Pedro, Naiol; Jungo, Sónia; Miguel, Avelina; Fortes-Gabriel, Elsa; Sebastião, CruzBackground: The impact of SARS-CoV-2 infection in Africa is still unclear. In comparison to Europe and North America, morbidity and death rates are lower. Several factors have been proposed, including geographical variation in virus impact, environmental factors, differences in age distribution, and the impact of infectious diseases such as malaria, HIV infection, and tuberculosis. Objectives: We investigated t...
Health literacy in hypertensive patients and adults without hypertension
Teixeira, Tânia; Saraiva Carvalho, Paula; Mendes Silva, Cláudia; Gama, JorgeHealth literacy plays a pivotal role in the management of chronic disease and access to health care. The present study aimed to evaluate and compare health literacy levels between adults with and without arterial hypertension. The research protocol included a sociodemographic questionnaire and the Health Literacy Survey in Portugal. The sample of this cross-sectional survey consisted of 152 participants, 76 of ...
Sensitisation to aeroallergens in relation to asthma and other allergic disease...
Arrais, Margarete; Lulua, Ofélia; Quifica, Francisca; Rosado-Pinto, José; Gama, Jorge; Brito, Miguel; Taborda-Barata, LuisIntroduction and Objectives: In Africa, few studies of sensitization profiles have been performed in children or adolescents and, in Angola, there are none. The objectives of the present study were to assess the sensitization profile of Angolan schoolchildren and to determine the relationship between that pattern, sociodemographic factors, asthma, and other allergic diseases. Materials and Methods: Cross-sectio...
Inhaler Technique Education and Exacerbation Risk in Older Adults with Asthma o...
Maricoto, Tiago; Monteiro, Luís; Gama, Jorge; Sousa, Jaime Correia de; Barata, Luis TabordaOBJECTIVES: To evaluate the effect of inhaler education programs on clinical outcomes and exacerbation rates in older adults with asthma or chronic obstructive pulmonary disease (COPD). DESIGN: Systematic review and meta-analysis. SETTING AND PARTICIPANTS: Older adults with asthma or COPD, either in primary or secondary health care and pharmacy setting. MEASUREMENTS: We searched the Medline, Embase, and Central...
Autoimmune hepatitis in 828 Brazilian children and adolescents: clinical and la...
Porta, Gilda; Carvalho, Elisa; Santos, Jorge Luiz Dos; Gama, Jorge; Borges, Cristian V.; Seixas, Renata; Ferreira, Alexandre; Miura, Irenesentation, laboratory findings, histological profile, treatments, and outcomes of children andadolescents with autoimmune hepatitis.Methods: The medical records of 828 children and adolescents with autoimmune hepatitiswere reviewed. A questionnaire was used to collect anonymous data on clinical presentation,biochemical and histological findings, and treatments.Results: Of all patients, 89.6% had autoimmune hepa...
Immunotherapy in Allergic Asthma – 5 year analysis: Is it a curative approach?
Costa, J. Coutinho; Machado, João Neiva; Ferreira, C.; Gama, Jorge; Almeida, T.; Arrobas, A.M.Asthma is a common, chronic and heterogeneous disease;it affects people of all ages and there has been a recentincrease in its prevalence and severity. It may be mild,barely noticed by the patient, or it may range all the way tovery severe disease, causing constant symptoms that greatlyaffect the quality life of the patient. [...]
Tobacco smoke as a risk factor for allergic sensitization in adults
Mónico, Beatriz; Gama, Jorge; Pastorinho, M. Ramiro; Lourenço, OlgaAllergic sensitization to aeroallergens is a common phenomenon and a crucial step in the development of allergic diseases. Nonetheless, the influence of tobacco smoke exposure on the development of allergic sensitization in adults is quite complex and not totally understood. [...]
Validation of NoSAS (Neck, Obesity, Snoring, Age, Sex) score as a screening too...
Coutinho Costa, J.; Rebelo-Marques, A.; Machado, João Neiva; Gama, Jorge; Santos, C.; Teixeira, F.; Moita, J.Screening methods have become increasingly important due to the growing number of patients suspected of having obstructive sleep apnea (OSA) being referred to sleep clinics. The Lausanne NoSAS (Neck circumference, Obesity, Snoring, Age, Sex) score test is a simple, efficient, and easily employed tool enabling identification of individuals at risk for the disease. The score ranges from 0 to 17 and the patient ha...
Prevalence and risk factors for food allergy in older people: protocol for a sy...
Dias, Inês Laia; Lozoya-Ibáñez, Carlos; Skypala, Isabel; Gama, Jorge; Nurmatov, Ulugbek; Lourenço, Olga; Barata, Luis TabordaStudies suggest that the prevalence of food allergy may be increasing worldwide. Results regarding the prevalence and features of adverse food reactions older people have, however, scarcely been analysed in the literature. Thus, the objective of the present systematic review will be to describe the prevalence of food allergy in older individuals, its risk factors, clinical features, as well as the most frequent...