7 documents found, page 1 of 1
New silver(I) phosphino complexes: Evaluation of their potential as prospective...
Maldonado, Yndira Dolores; Scalese, Gonzalo; Manieri, Karyn Fernanda [UNESP]; Pavan, Fernando R. [UNESP]; Aguirre Méndez, Larry D.; Gambino, DinorahMade available in DSpace on 2022-05-01T11:07:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; Despite being a preventable and curable disease, Tuberculosis (TB) is the world's top infectious killer. Development of new drugs is urgently needed. In this work, the synthesis and characterization of new silver(I) complexes, that include N′-[(E)-(pyridine-2-ylmethylene)pyrazine-2-carbohydrazide, HPCPH...
Novel iron complexes with quinoxaline N-1,N-4-dioxide derivatives: synthesis, c...
Tarallo, M. Belen; Urquiola, Carolina; Monge, Antonio; Pavan, Fernando R. [UNESP]; Leite, Clarice Q. [UNESP]; Torre, Maria H.; Gambino, DinorahMade available in DSpace on 2020-12-10T22:01:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-01-01; CHLCC; PEDECIBA Quimica; Three new iron complexes with 3-aminoquinoxaline-2-carbonitrile N-1, N-4-dioxide derivatives (L) with stoichiometries [Fe(L1)(2)], [Fe(L1)(3)] and [Fe(L2)(3)]center dot 5H(2)O were synthesized and characterized. Both ligands and complexes showed in vitro activity against Mycobac...
Bactericidal effect of pyridine-2-thiol 1-oxide sodium salt and its complex wit...
Campos, Debora L. [UNESP]; Machado, Ignacio; Ribeiro, Camila M. [UNESP]; Gambino, Dinorah; Pavan, Fernando R. [UNESP]Made available in DSpace on 2020-12-12T01:44:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-02-01; The objective of this study was to determine the activity of pyridine-2-thiol 1-oxide sodium salt (Na mpo) and its complex with iron [Fe(mpo)3] against Mycobacterium tuberculosis. The compounds were tested against a standard strain of M. tuberculosis H37Rv (ATCC 27294), with minimal inhibitory concentra...
Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotox...
Rivas, Feriannys; Medeiros, Andrea; Comini, Marcelo; Suescun, Leopoldo; Rodríguez Arce, Esteban; Martins, Marta; Pinheiro, Teresa; Marques, FernandaSearching for a more effective chemotherapy for the treatment of Human African trypanosomiasis, the disease caused by the parasite Trypanosoma brucei, and cancer, in the current work five new [PtII(L)(dppf)](PF6) compounds, with HL = 8-hydroxyquinoline derivatives and dppf = 1,1'-bis(diphenylphosphino)ferrocene, were synthesized and fully characterized. Crystal structures of three compounds were solved by XRD. ...
New heterobimetallic ferrocenyl derivatives: Evaluation of their potential as p...
Rivas, Feriannys; Medeiros, Andrea; Rodríguez Arce, Esteban; Comini, Marcelo; Ribeiro, Camila M. [UNESP]; Pavan, Fernando R. [UNESP]; Gambino, DinorahMade available in DSpace on 2018-12-11T17:37:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-10-01; Agencia Nacional de Investigación e Innovación; Searching for prospective agents against infectious diseases, four new ferrocenyl derivatives, [M(L)(dppf)4](PF6), with M = Pd(II) or Pt(II), dppf = 1,1′-bis(dipheny1phosphino) ferrocene and HL = tropolone (HTrop) or hinokitiol (HHino), were synthesized an...
Bioactivity of pyridine-2-thiolato-1-oxide metal complexes: Bi(III), Fe(III) an...
MacHado, Ignacio; Marino, Leonardo Biancolino [UNESP]; Demoro, Bruno; Echeverría, Gustavo A.; Piro, Oscar E.; Leite, Clarice Q.F. [UNESP]Made available in DSpace on 2018-12-11T17:24:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-11-24; In the search for new therapeutic tools against tuberculosis and to further address the therapeutic potential of pyridine-2-thiol 1-oxide (Hmpo) metal complexes, two new octahedral [M<sup>III</sup>(mpo)<inf>3</inf>] complexes, withM Combining double low line Ga or Bi, were synthesized and characterized ...
Design of novel iron compounds as potential therapeutic agents against tubercul...
Gambino, Dinorah