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Systemic inflammation as a risk factor for portal vein thrombosis in cirrhosis:...

Nery, F; Carneiro, P; Correia, S; Macedo, C; Gandara, J; Lopes, V; Valadares, D; Ferreira, S; Oliveira, J; Teixeira Gomes, M; Miranda, HP; Rautou, PE

Background and Aims Various risk factors for portal vein thrombosis (PVT) development in patients with cirrhosis have been identified, but the role of systemic inflammatory reaction is unknown. The study aims to assess the association between markers of systemic inflammation and PVT in cirrhosis. Methods Between January 2014 and October 2015, 107 outpatients with cirrhosis and no PVT were recruited, and followe...


Acquired hepatocerebral degeneration and hepatic encephalopathy: one or two ent...

Malaquias, MJ; Pinto, CM; Ramos, C; Ferreira, S; Gandara, J; Almeida, A; Cavaco, S; Miranda, HP; Magalhães, M

Background and purpose: Acquired hepatocerebral degeneration (AHD) and hepatic encephalopathy (HE) are neurological complications of chronic liver disease (CLD) with portosystemic shunt. While HE is common, AHD is a rare entity, and the clinical imaging relationships observed in small series lack validation in large patient cohorts. The aim of this study was to characterize a cohort of AHD patients and to explo...


Nonselective beta-blockers and the risk of portal vein thrombosis in patients w...

Nery, F; Correia, S; Macedo, C; Gandara, J; Lopes, V; Valadares, D; Ferreira, S; Oliveira, J; Gomes, MT; Lucas, R; Rautou, PE; Miranda, HP; Valla, D

Background Nonmalignant portal vein thrombosis is a significant event in the course of cirrhosis that can contraindicate liver transplantation and even impact survival after the surgical procedure. Risk factors are not completely known or validated and are still debated. Aim To identify in patients with cirrhosis the risk factors for portal vein thrombosis that are assessable in clinical practice. Methods Betwe...


Liver transplant recipients have a higher prevalence of anal squamous intraepit...

Albuquerque, G; Miranda, HP; Lopes, J; Gandara, J; Rodrigues, S; Gaspar, R; Morais, R; Ramalho, R; Rodrigues-Pinto, E; Cardoso, H; Barroca, H; Dias, CC

Background: Anal squamous intraepithelial lesions (ASIL) are precancerous lesions of anal squamous cell carcinoma, with a higher prevalence in immunosuppressed patients. There are some studies in kidney transplant recipients, but there is no information regarding prevalence in liver transplantation. Our aim was to evaluate the prevalence of ASIL in this setting. Methods: Prospective case–control study involving...


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