Gardner syndrome (GS) is a rare autosomal dominant disorder that can present with craniomaxillofacial abnormalities. The identification of osteomas or craniomaxillofacial abnormalities can therefore serve as a marker of this condition, facilitating early referral and diagnosis. A 17-year-old female with GS was referred for the management of severe limited mouth opening, causing a major problem for routine endos...
O sentimento de pertença e inclusão são conceitos essenciais na sociedade e determinantes em ambientes educativos. Como a peteca (P) é um brinquedo indígena brasileiro, analisámos numa classe do 1º Ciclo do Ensino Básico (CEB) (N=16, 106,6±10,3 meses; meninas=9; meninos=6), o comportamento de crianças de origem brasileira (B) (n= 8) e de outras nacionalidades (portuguesa e indiana) (D), perante o desafio de con...
Too little is known about areia de escrever, i.e., blotting sands, the intriguing particles sprinkled on freshly written scripts to accelerate the drying time of the ink. Blotting sands constitute a valuable but underestimated historical source. This work investigated the blotting sands used on the account books of the religious houses scattered across continental Portugal and Madeira Island (16th-19th centurie...
Historical and archival research focused on the Portuguese Inquisition documents (1551–1800) uncovered the use of arena known as blotting sands, a writing accessory used to hasten ink drying. We present in this work the first systematic study combining image analysis, SEM/EDS and μ-Raman techniques, statistics and chemometrics to characterise the blotting sands used by the Portuguese Inquisition and hypothesise...
Background: Designing reliable in vitro assays is crucial to attain impactful results in oncology research. Cell Microarray (CMA) has become a key tool to accelerate cancer research as many samples can be evaluated at the same time in a single slide, allowing the evaluation of many prognostics, diagnostics, and therapy response biomarkers. Previously, we described a model of drug combination using antineoplasti...
Cardiovascular diseases (CVDs) account for a significant portion of global mortality, emphasizing the need for effective strategies. This study focuses on myocardial infarction, pulmonary thromboembolism, and aortic stenosis, aiming to empower medical practitioners with tools for informed decision making and timely interventions. Drawing from data at Hospital Santa Maria, our approach combines exploratory data ...
The study here presented aimed to characterize two ambrotypes from the 19th century and some of their degradation patterns using an in-situ analytical approach, minimally invasive, composed by technical photography and optical microscopy under different illumination, scanning electron microscopy with energy dispersive spectroscopy coupled (SEM-EDS) and micro-Fourier transform infrared spectroscopy (μ-FT-IR). Mi...
Technology has changed many aspects of life in society, playing a key role in our quotidian, and having profound impacts on how we relate to our peers and the way we educate the youngest. Collaborative tools have broken the barriers of time and space, allowing us to collaborate without these constraints. There are numerous advantages in the use of these tools in secondary education both in the immediate and fut...
Introduction: Vitamin C is a water-soluble vitamin necessary for the synthesis of collagen and muscle carnitine, absorption of iron from non-heme iron sources, among others (1). Fruits and vegetables naturally contain high levels of vitamin C (2). The oxidation of L-ascorbic acid in dehydroascorbic acid is common in the presence of oxygen, light, temperature, high pressures, and alkaline pH (3). In this study, ...