13 documents found, page 1 of 2
Microalgae as potential sources of bioactive compounds for functional foods and...
Silva, Mélanie; Kamberovic, Farah; Uota, Sisay Tesema; Kovan, Ismael-Mohammed; Viegas, Carla; Simes, D; Gangadhar, Katkam N.; João, VarelaMicroalgae are an untapped source of bioactive compounds with various biotechnological applications. Several species are industrially produced and commercialized for the feed or cosmetic industries, however, other applications in the functional food and pharmaceutical markets can be foreseen. In this study, nine industrial/commercial species were evaluated for in vitro antioxidant, calcium-chelating, anti-tumor...
Anti-Hepatocellular Carcinoma (HepG2) Activities of Monoterpene Hydroxy Lactone...
Gangadhar, Katkam N.; Rodrigues, Maria João; Pereira, Hugo; Gaspar, Helena; Malcata, F. Xavier; Barreira, Luísa; Varela, JoãoTisochrysis lutea is a marine haptophyte rich in omega-3 polyunsaturated fatty acids (e.g., docosahexaenoic acid (DHA)) and carotenoids (e.g., fucoxanthin). Because of the nutraceutical applications of these compounds, this microalga is being used in aquaculture to feed oyster and shrimp larvae. In our earlier report, T. lutea organic crude extracts exhibited in vitro cytotoxic activity against human hepatocarc...
Anti-Hepatocellular Carcinoma (HepG2) activities of Monoterpene Hydroxy Lactone...
Gangadhar, Katkam N.; Rodrigues, Maria Joao; Pereira, Hugo; Gaspar, Helena; Malcata, F. Xavier; Barreira, Luísa; Varela, JoãoTisochrysis lutea is a marine haptophyte rich in omega-3 polyunsaturated fatty acids (e.g., docosahexaenoic acid (DHA)) and carotenoids (e.g., fucoxanthin). Because of the nutraceutical applications of these compounds, this microalga is being used in aquaculture to feed oyster and shrimp larvae. In our earlier report, T. lutea organic crude extracts exhibited in vitro cytotoxic activity against human hepatocarc...
Nutritional potential and toxicological evaluation of tetraselmis sp. CTP4 micr...
Pereira, Hugo; Silva, Joana; Santos, Tamara; Gangadhar, Katkam N.; Raposo, Ana; Nunes, Cláudia; Coimbra, Manuel A.; Gouveia, Luísa; Barreira, LuísaCommercial production of microalgal biomass for food and feed is a recent worldwide trend. Although it is common to publish nutritional data for microalgae grown at the lab-scale, data about industrial strains cultivated in an industrial setting are scarce in the literature. Thus, here we present the nutritional composition and a microbiological and toxicological evaluation of Tetraselmis sp. CTP4 biomass, cult...
Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira bac...
Bruno de Sousa, Carolina; Gangadhar, Katkam N.; Morais, Thiago R.; Conserva, Geanne A.A.; Vizetto-Duarte, Catarina; Pereira, Hugo; Laurenti, Márcia D.Made available in DSpace on 2018-12-11T17:09:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-03-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The development of novel drugs for the treatment of leishmaniases continues to be crucial to overcome the severe impacts of these diseases on human and animal health. Seve...
Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira bac...
Sousa, Carolina Bruno de; Gangadhar, Katkam N.; Morais, Thiago R.; Conserva, Geanne A. A.; Vizetto-Duarte, C; Pereira, H.; Laurenti, Marcia D.The development of novel drugs for the treatment of leishmaniases continues to be crucial to overcome the severe impacts of these diseases on human and animal health. Several bioactivities have been described in extracts from macroalgae belonging to the Cystoseira genus. However, none of the studies has reported the chemical compounds responsible for the antileishmanial activity observed upon incubation of the ...
Urban wastewater treatment by Tetraselmis sp CTP4 (Chlorophyta)
Schulze, Peter S.C.; Carvalho, Carolina F. M.; H., Pereira; Gangadhar, Katkam N.; Lisa Schueler, Lisa M. Schueler; Santos, Tamara; Varela, J.The ability of a recent isolate, Tetraselmis sp. CTP4, for nutrient removal from sewage effluents before and after the nitrification process under batch and continuous cultivation was studied. Biomass productivities in both wastewaters were similar under continuous conditions ( 0.343 +/- 0.053 g L-1 d(-1)) and nutrient uptake rates were maximal 31.4 +/- 0.4 mg N L-1 d(-1) and 6.66 +/- 1.57 mg P-PO43 L- 1 d(-1) ...
Assessment and comparison of the properties of biodiesel synthesized from three...
Gangadhar, Katkam N.; Pereira, Hugo; Diogo, Herminio P.; Borges dos Santos, R. M.; Devi, B. L. A. Prabhavathi; Prasad, R. B. N.; Custódio, LuísaIn recent years, microalgae-based carbon-neutral biofuels (i.e., biodiesel) have gained considerable interest due to high growth rate and higher lipid productivity of microalgae during the whole year, delivering continuous biomass production as compared to vegetable-based feedstocks. Therefore, biodiesel was synthesized from three different microalgal species, namely Tetraselmis sp. (Chlorophyta) and Nannochlor...
Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira t...
Vizetto-Duarte, C; Custódio, Luísa; Gangadhar, Katkam N.; Lago, João Henrique G.; Dias, Catarina; Matos, Ana Marta; Neng, NunoBackground: Brown macroalgae have attracted attention because they display a wide range of biological activities, including antitumoral properties. In this study we isolated isololiolide from Cystoseira tamariscifolia for the first time.Purpose: To examine the therapeutical potential of isololiolide against tumor cell lines.Methods/Study design: The structure of the compound was established and confirmed by 1D ...
Isolation of a euryhaline microalgal strain, Tetraselmis sp CTP4, as a robust f...
Pereira, Hugo; Gangadhar, Katkam N.; Schulze, Peter S.C.; Santos, Tamara; de Sousa, Carolina Bruno; Schueler, Lisa; Custódio, Luísa; Malcata, F. XavierBioprospecting for novel microalgal strains is key to improving the feasibility of microalgae-derived biodiesel production. Tetraselmis sp. CTP4 (Chlorophyta, Chlorodendrophyceae) was isolated using fluorescence activated cell sorting (FACS) in order to screen novel lipid-rich microalgae. CTP4 is a robust, euryhaline strain able to grow in seawater growth medium as well as in non-sterile urban wastewater. Becau...