From the leaves of Solanum campaniforme (Solanaceae), eight solanidane alkaloids were isolated, four of which contain a p-hydroxyphenylethylamine unit. Their structures were established as: 22b,23b-epoxysolanida- 1,4-dien-3-one; 22a,23a-epoxy-10-epi-solanida-1,4,9-trien-3-one; 22a,23a-epoxy-solanida-4- en-3-one; 22b,23b-epoxy-solanida-4-en-3-one; (E)-N-[80(4-hydroxyphenyl)ethyl]-22a,23a-epoxy-solanida-1, 4,9-tr...
Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:30:52Z No. of bitstreams: 0; Made available in DSpace on 2014-05-27T11:30:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-11-01; Mammalian natriuretic peptides (NPs) have been extensively investigated for use as therapeutic agents in the treatment of cardiovascular diseases. Here, we describe the isolation, sequ...