8 documents found, page 1 of 1
Dietary acrylamide in human health
Laguzzi, Federica; Filippini, Tommaso; Virgolino, AnaAcrylamide, a food processing contaminant, has raised concerns due to potential health risks to humans. It is known to be formed mainly in starch-rich foods, cooked or processed at high temperatures (above 120°C) in the absence of moisture, via the Maillard reaction when a reduced carbohydrate (glucose and fructose) combines with the amino acid asparagine. Moreover, evidence suggests that acrylamide may also fo...
Harmonized human biomonitoring in European children, teenagers and adults: EU-w...
Govarts, Eva; Gilles, Liese; Rodriguez Martin, Laura; Santonen, Tiina; Apel, Petra; Alvito, Paula; Anastasi, Elena; Andersen, Helle RaunAs one of the core elements of the European Human Biomonitoring Initiative (HBM4EU) a human biomonitoring (HBM) survey was conducted in 23 countries to generate EU-wide comparable HBM data. This survey has built on existing HBM capacity in Europe by aligning national or regional HBM studies, referred to as the HBM4EU Aligned Studies. The HBM4EU Aligned Studies included a total of 10,795 participants from three ...
Implementation of effect biomarkers in human biomonitoring studies: A systemati...
Rodríguez-Carrillo, Andrea; Mustieles, Vicente; Salamanca-Fernández, Elena; Olivas-Martínez, Alicia; Suárez, Beatriz; Bajard, Lola; Baken, KirstenHuman biomonitoring (HBM) studies have highlighted widespread daily exposure to environmental chemicals. Some of these are suspected to contribute to adverse health outcomes such as reproductive, neurological, and metabolic disorders, among other developmental and chronic impairments. One of the objectives of the H2020 European Human Biomonitoring Initiative (HBM4EU) was the development of informative effect bi...
Harmonized human biomonitoring in European children, teenagers and adults: EU-w...
Govarts, Eva; Gilles, Liese; Rodriguez Martin, Laura; Santonen, Tiina; Apel, Petra; Alvito, Paula; Anastasi, Elena; Andersen, Helle RaunAbstract: As one of the core elements of the European Human Biomonitoring Initiative (HBM4EU) a human biomonitoring (HBM) survey was conducted in 23 countries to generate EU-wide comparable HBM data. This survey has built on existing HBM capacity in Europe by aligning national or regional HBM studies, referred to as the HBM4EU Aligned Studies. The HBM4EU Aligned Studies included a total of 10,795 participants o...
Trends of Exposure to Acrylamide as Measured by Urinary Biomarkers Levels withi...
Poteser, Michael; Laguzzi, Federica; Schettgen, Thomas; Vogel, Nina; Weber, Till; Murawski, Aline; Schmidt, Phillipp; Rüther, MariaAcrylamide, a substance potentially carcinogenic in humans, represents a very prevalent contaminant in food and is also contained in tobacco smoke. Occupational exposure to higher concentrations of acrylamide was shown to induce neurotoxicity in humans. To minimize related risks for public health, it is vital to obtain data on the actual level of exposure in differently affected segments of the population. To a...
Time Trends of Acrylamide Exposure in Europe: Combined Analysis of Published Re...
Poteser, Michael; Laguzzi, Federica; Schettgen, Thomas; Vogel, Nina; Weber, Till; Zimmermann, Philipp; Hahn, Domenica; Kolossa-Gehring, MarikeMore than 20 years ago, acrylamide was added to the list of potential carcinogens found in many common dietary products and tobacco smoke. Consequently, human biomonitoring studies investigating exposure to acrylamide in the form of adducts in blood and metabolites in urine have been performed to obtain data on the actual burden in different populations of the world and in Europe. Recognizing the related health...
Dietary acrylamide exposure and risk of site-specific cancer: a systematic revi...
Filippini, Tommaso; Halldorsson, Thorhallur I.; Capitão, Carolina; Martins, Raquel; Giannakou, Konstantinos; Hogervorst, Janneke; Vinceti, MarcoDiet is a main source of acrylamide exposure to humans. Existing observational data on the relationship between dietary exposure to acrylamide and risk of cancer are inconsistent. We performed a systematic review and dose-response meta-analysis of epidemiological studies evaluating the association between dietary acrylamide exposure and several site-specific cancer. A systematic literature search was conducted ...
Maternal acrylamide exposure during pregnancy and fetal growth: a systematic re...
Hogervorst, Janneke; Virgolino, Ana; Halldorsson, Thorhallur I.; Vinceti, Marco; Åkesson, Agneta; Leander, Karin; Nawrot, Tim; Filippini, TommasoBackground: Acrylamide is a food contaminant linked to developmental toxicity in animals and possibly in humans. Objectives: We performed a systematic review and dose-response meta-analysis of epidemiological studies evaluating the relationship between maternal acrylamide exposure during pregnancy and the risk of being small for gestational age (SGA) and birth weight, birth head circumference and birth length. ...