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Surface Functionalization of PLGA Nanoparticles to Increase Transport across th...

Del Amo, Laura; Cano, Amanda; Ettcheto, Miren; Souto, Eliana B.; Espina, Marta; Camins, Antoni; García, Maria Luísa; Sánchez-López, Elena

Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that accounts for about 60% of all diagnosed cases of dementia worldwide. Although there are currently several drugs marketed for its treatment, none are capable of slowing down or stopping the progression of AD. The role of the blood-brain barrier (BBB) plays a key role in the design of a successful treatment for this neurodegenerative disease. N...


Surface functionalization of PLGA nanoparticles to increase transport across th...

Del Amo, Laura; Cano, Amanda; Ettcheto, Miren; Souto, Eliana B.; Espina, Marta; Camins, Antoni; García, Maria Luísa; Sánchez-López, Elena

Alzheimers disease (AD) is a chronic neurodegenerative disorder that accounts for about 60% of all diagnosed cases of dementia worldwide. Although there are currently several drugs marketed for its treatment, none are capable of slowing down or stopping the progression of AD. The role of the blood-brain barrier (BBB) plays a key role in the design of a successful treatment for this neurodegenerative disease. Na...


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