26 documents found, page 1 of 3

Innovative processing and sterilization techniques to unlock the potential of s...

Silk sericin (SS), a by-product of the textile industry, has gained significant attention for its biomedical potential due to its biocompatibility and regenerative potential. However, the literature lacks information on SS processing methods and the resulting physicochemical properties. This study represents the first step in protocol optimization and standardization. In the present work, different processing t...

Silk fibroin microparticles as a candidate for wound healing applications: eval...

In this study, silk fibroin (SF) aerogel microparticles were developed as a delivery system for adenosine (ADO) to exploit its anti-inflammatory and regenerative properties for wound healing. Supercritical CO2 drying was used to prepare ADO-loaded SF aerogel microparticles with different SF concentrations (3 %, 5 %, 7 % w/v) and SF: ADO ratios (10:1, 5:1, 2:1). Characterization revealed high porosity (91–94 %),...

Expanding the potential of self-assembled silk fibroin as aerogel particles for...

A newly produced silk fibroin (SF) aerogel particulate system using a supercritical carbon dioxide (scCO2)-assisted drying technology is herein proposed for biomedical applications. Different concentrations of silk fibroin (3%, 5%, and 7% (w/v)) were explored to investigate the potential of this technology to produce size- and porosity-controlled particles. Laser diffraction, helium pycnometry, nitrogen adsorpt...

Adenosine-loaded silk fibroin: a promising approach for chronic wound healing a...

Introduction: Chronic wounds are one of the major therapeutic and healthcare challenges affecting the population globally. During the healing stage of a wound the production of exudate is considered as a normal process. However, its overproduction can compromise and delay the inflammatory phase, contributing to wound chronicity. Aerogels are highly porous materials which can provide advanced performance for wou...

Sustainable silk-based particulate systems for the controlled release of pharma...

The increasing demand for innovative approaches in wound healing and skin regeneration has prompted extensive research into advanced biomaterials. This review focuses on showcasing the unique properties of sustainable silk-based particulate systems in promoting the controlled release of pharmaceuticals and bioactive agents in the context of wound healing and skin regeneration. Silk fibroin and sericin are deriv...

Poly(ionic liquid)-based aerogels for continuous-flow CO2 upcycling

The atmospheric concentration of CO2 is rising at an alarming pace, creating a pressing need for new and sustainable materials capable of capture and conversion. Poly(ionic liquid)s (PILs) are particularly effective catalysts for processes at or near atmospheric pressure. PILs industrial application poses challenges due to the low porosity of PIL, the limited batch conversion capacity, and the difficulties in r...

Unleashing the healing potential of adenosine: advanced silk fibroin aerogel fo...

In vitro assessment of silk fibroin aerogel particles loaded with adenosine for...

Development of self-assembled silk fibroin particles for wound healing

Supercritical CO2 technology for the fabrication of silk fibroin aerogel partic...