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Estudo químico das folhas de Trichilia silvatica (Meliaceae)

Soares,Aloízio de Oliveira; Ferreira,Adrienn Gianny Leguizamon; Soares,Luzinátia Ramos; Corsino,Joaquim; Garcez,Fernanda Rodrigues; Garcez,Walmir Silva

From the leaves of a specimen of Trichilia silvatica Meliaceae, eight known compounds were isolated, namely, two pregnanes, 2α,3β,4β-trihydroxypregnan-16-one (1) and 2β,3β,4β-trihydroxypregnan-16-one (2), three diterpenes, cneorubine X (3), kolavelool (4) and kolavenol (5), in addition to γ-tocopherol, 3-O-β-D-glucopyranosyl-β-sitosterol and 3-O-β-D-glucopyranosyl-stigmasterol. This is the first reported occurr...

Date: 2014   |   Origin: Oasisbr

Sesquiterpenos e outros constituintes das folhas de Pterodon pubescens Benth (L...

Miranda,Mayker Lazaro Dantas; Garcez,Fernanda Rodrigues; Abot,Alfredo Raúl; Garcez,Walmir Silva

In addition to β-sitosterol, stigmasterol, phaeophitin A, luteolin, kaempferol, quercetin, (+)-catechin, quercetin-3-O-α-L-rhamnopyranoside, rutin, and p-hydroxy-benzoic acid, six known sesquiterpenes, namely (rel)-2β,6β-epoxy-5β-hydroxy-isodaucane, oplopanone, 1β,6α-dihydroxy-4(15)-eudesmene, caryophyllene oxide, α-cadinol, and spathulenol, were isolated from the leaves of Pterodon pubescens (Leguminosae) grow...

Date: 2014   |   Origin: Oasisbr

Pregnanos e outros constituintes das raízes de Macrosiphonia petraea (A. St.-Hi...

Assis Junior,Luiz Roberto de; Garcez,Fernanda Rodrigues; Garcez,Walmir Silva; Guterres,Zaira da Rosa

Macrosiphonia petraea (A. St.-Hil.) Kuntze is a plant popularly known as "velame". Its root infusion is used in the folk medicine of Mato Grosso do Sul, Brazil, for the treatment of inflammatory diseases. Phytochemical investigation of the roots of this species led to the identification of 17 compounds belonging to four different classes: two pregnanes, 12β-hydroxypregna-4,6,16-triene-3,20-dione, neridienone A,...

Date: 2013   |   Origin: Oasisbr

Sesquiterpenos de Ocotea lancifolia (Lauraceae)

Camargo,Maria José de; Miranda,Mayker Lazaro Dantas; Kagamida,Camila Miyuki; Rodrigues,Edilene Delphino; Garcez,Fernanda Rodrigues; Garcez,Walmir Silva

Six new eremophilane sesquiterpenes, (rel)-4β,5β,7β-eremophil-9-en-12-oic acid (1), (rel)-4β,5β,7β-eremophil-1(10)-en-12-oic acid (2), (rel)-4β,5β,7β-eremophil-1(10)-en-2-oxo-12-oic acid (3), (rel)-4β,5β,7β-eremophil-9-en-12,8α-olide (4), (rel)-4β,5β,7β-eremophil-9-en-12,8β-olide (5) and (rel)-4β,5β,7β-eremophil-9α,10α-epoxy-12-oic acid (6), were isolated from the leaves of a specimen of Ocotea lancifolia (Laur...

Date: 2013   |   Origin: Oasisbr

Antimicrobial activity of some medicinal plants from the cerrado of the central...

Violante,Ivana Maria Póvoa; Hamerski,Lidilhone; Garcez,Walmir Silva; Batista,Ana Lucia; Chang,Marilene Rodrigues; Pott,Vali Joana

Ethanol extracts from six selected species from the Cerrado of the Central-Western region of Brazil, which are used in traditional medicine for the treatment of infectious diseases and other medical conditions, namely Erythroxylum suberosum St. Hil. (Erythroxylaceae), Hyptis crenata Pohl. ex Benth. (Lamiaceae), Roupala brasiliensis Klotz. (Proteaceae), Simarouba versicolor St. Hil. (Simaroubaceae), Guazuma ulmi...

Date: 2012   |   Origin: Oasisbr

Sesquiterpenos de sementes de Guarea guidonia (Meliaceae)

Soares,Luzinátia Ramos; Silva,Alene Cortes de Queiroz e; Freire,Talita Vilalva; Garcez,Fernanda Rodrigues; Garcez,Walmir Silva

Two new sesquiterpenes 6α-ethoxyeudesm-4(15)-en-1β-ol (1) and (7R*)-5-epi-opposit-4(15)-ene-1β,7-diol (7) were isolated from the seeds of a specimen of Guarea guidonia (Meliaceae). Five other known sesquiterpenes, eudesm-4(15)-ene-1β,6α-diol (2), 5-epi-eudesm-4(15)-ene-1β,6β-diol (3), eudesm-4(15)-ene-1β,5α-diol (4), eudesm-4(15),7-dien-1β-ol (5) and (7R*)-opposit-4(15)-ene-1β,7-diol (6), were also isolated in ...

Date: 2012   |   Origin: Oasisbr

Constituintes químicos das folhas de Riedeliella graciliflora Harms (Leguminosae)

Miranda,Mayker Lazaro Dantas; Souza,Alex Fonseca; Rodrigues,Edilene Delphino; Garcez,Fernanda Rodrigues; Garcez,Walmir Silva; Abot,Alfredo

A new salicylic acid derivative, pentacosanyl salicylate, was isolated from the leaves of the plant toxic to cattle, Riedeliella graciliflora, in addition to a digalactosyldiacylglycerol (DGDG), 1,2-di-O-α-linolenoyl-3-O-α-D-galactopyranosyl-(1→6)-β-D-galactopyranosyl-glycerol, kaempferol-3-O-β-D-glucopyranoside, kaempferol-3-O-α-L-rhamnopyranoside, quercetin-3-O-α-L-rhamnopyranoside, rutin, (+)-catechin and th...

Date: 2012   |   Origin: Oasisbr

16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia

Garcez,Walmir Silva; Garcez,Fernanda Rodrigues; Soares,Luzinátia Ramos

Two new seco- and di-seco-pregnanes, 2α,3β-dihydroxy-16,17-seco-pregn-17-ene-16-oic acid methyl ester 2β,19-hemiketal (1) and 2,3:16,17-di-seco-pregn-17-ene-3-oic acid-16-oic acid methyl ester-19-hydroxy-2-carboxylic acid-2,19-lactone (2), have been obtained from the trunk bark of Guarea guidonia. Their structures have been established by a combination of 1D- and 2D-NMR spectroscopic techniques and MS data. The...

Date: 2008   |   Origin: Oasisbr

Novos constituintes químicos das cascas do caule de Tabebuia heptaphylla

Garcez,Fernanda Rodrigues; Garcez,Walmir Silva; Mahmoud,Talal Suleiman; Figueiredo,Patrícia de Oliveira; Resende,Ubirazilda Maria

A new triterpene, 3beta,6beta,21beta-trihydroxyolean-12-ene and a new iridoid, 8alpha-methyl-8beta-hydroxy-6beta-(3',4'-dimethoxy)benzoyloxy-1 alpha,3alpha-dimethoxy-octahydro-cyclopenta[c]pyran were isolated from the trunk bark of a specimen of Tabebuia heptaphylla (Bignoniaceae) collected in the "Pantanal" of Mato Grosso do Sul, Brazil. Twelve known compounds were also obtained in this work, comprising four i...

Date: 2007   |   Origin: Oasisbr

Estudo fitoquímico de Unonopsis lindmanii - Annonaceae, biomonitorado pelo ensa...

Siqueira,João Máximo de; Bomm,Mauro Dionei; Pereira,Núbia Fernanda Gomes; Garcez,Walmir Silva; Boaventura,Maria Amélia Diamantino

Extracts obtained from leaves, seeds and bark of Unonopsis lindmanii were evaluated by means of Brine Shrimp Lethality test (BSL). Through bioassay-guided chromatographic fractionation, liriodenine, an oxoaporphine alkaloid, was isolated from the bark extracts as the bioactive compound. Two additional inactive known alkaloids, unonopsine and lysicamine were also isolated from the bark extracts.

Date: 1998   |   Origin: Oasisbr

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