13 documents found, page 1 of 2

COVID-19 in a Tertiary Paediatric Centre in Portugal: a Single-Centre Retrospec...

Objective: To describe the demographic, clinical, laboratory and imaging features of the first 300 SARS-CoV-2-infected children presenting to a tertiary paediatric centre in Portugal. Design: Single-centre, retrospective, descriptive study of paediatric patients who had a confirmed SARS-CoV-2 infection from 7 March to 20 September 2020. Setting: Tertiary paediatric referral centre (Hospital Dona Estefânia, Lisb...

Diagnostic Challenge in a Sickle Cell Disease Patient with COVID-19

Acute chest syndrome is a life-threatening complication in sickle cell disease. Infections are frequently implied, and like other viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be a trigger. In addition, due to their inflammatory status, they may present a higher risk for severe coronavirus disease 2019 (COVID-19). Pneumonia and acute chest syndrome share clinical, laboratory, and rad...

Multisystem Inflammatory Syndrome in Children Associated with COVID-19 in a Ter...

Introduction: Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe manifestation of coronavirus disease 2019 (COVID-19). The aim of this study was to describe the characteristics of children with MIS-C admitted to a pediatric tertiary hospital in Portugal. Material and methods: Observational descriptive study of MIS-C patients admitted between April 2020 and April 2021. Demographic and cli...

Protocol-Based Cardiotoxicity Monitoring in Hydroxychloroquine Medicated COVID-...

Introduction/objectives: By May 2020, SARS-CoV-2 had caused more than 400 000 deaths worldwide. Initially, hydroxychloroquine was a treatment option for COVID-19. More recent studies have questioned its safety and efficacy and, until stronger evidence is available, it was suspended from therapy protocols. We describe our experience treating COVID-19 Portuguese pediatric patients with hydroxychloroquine, having ...

Cardiac Injury and Vasoplegia in Critically ill Children due to Multisystem Inf...

Saliva Molecular Testing Bypassing RNA Extraction is Suitable for Monitoring an...

Background: Adults are being vaccinated against SARS-CoV-2 worldwide, but the longitudinal protection of these vaccines is uncertain, given the ongoing appearance of SARS-CoV-2 variants. Children remain largely unvaccinated and are susceptible to infection, with studies reporting that they actively transmit the virus even when asymptomatic, thus affecting the community. Methods: We investigated if saliva is an ...

Clinical and Therapeutic Approach to Hospitalized COVID-19 Patients: A Pediatri...

Introduction: Coronavirus disease 2019, or COVID-19, in children is usually a mild disease, but severe illness has been reported. Currently, the therapy benefits of antiviral experimental drugs are still uncertain. The main aim of this study is to describe the experience of a level III hospital regarding therapeutic management of hospitalized children with COVID-19 and to characterize clinical features and evol...

Acute Haemorrhagic Oedema of Infancy as a Manifestation of COVID-19

‘TB OR NOT TB?’: The Importance of Appropriate Screening

Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara

A mononucleose infeciosa é uma das principais manifestações clínicas da infeção pelo vírus Epstein-Barr. Nesta síndrome, a elevação das aminotransferases é comum mas a colestase é rara, havendo poucos casos descritos na literatura. Adolescente, 14 anos, sexo feminino, admitida no serviço de urgência por febre, odinofagia e adenomegália cervical. Iniciou tratamento com amoxicilina e dois dias depois iniciou icte...