4 documents found, page 1 of 1
High efficient strategy for the production of hydroxyapatite/silk sericin nanoc...
Veiga, A.; F. Castro; Oliveira, AL; Fernando RochaBACKGROUND Sericin (SS) induces nucleation of bone-like hydroxyapatite (HAp) when used as an organic matrix. HAp/SS nanocomposites have been conventionally synthesized through precipitation in stirred tank reactors (STs). Despite its simplicity, this process is time consuming and presents difficulties in scale-up. In our study, HAp/SS nanocomposites were successfully synthesized in a ST and in a meso-oscillator...
Bioaerogels: Promising nanostructured materials in fluid management, healing an...
Bernardes, BG; Del Gaudio, P; Alves, P; Costa, R; García-Gonzaléz, CA; Oliveira, ALWounds affect one’s quality of life and should be managed on a patient-specific approach, based on the particular healing phase and wound condition. During wound healing, exudate is produced as a natural response towards healing. However, excessive production can be detrimental, representing a challenge for wound management. The design and development of new healing devices and therapeutics with improved perfor...
SAPHO: Has the Time Come for Tailored Therapy?
Figueiredo, AS; Oliveira, AL; Caetano, A; Moraes-Fontes, MFSAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome is a heterogeneous condition combining osteoarticular and cutaneous manifestations. Conventional treatments are mostly ineffective. We hereby report two patients, the first with an aggressive form of disease and the second with an incomplete response to two different anti-TNF-α agents. Both were successfully treated with tocilizumab and ust...
Paradoxical Pulmonary Event Under Tocilizumab Treatment for Systemic Sclerosis-...
Oliveira, AL; Ruano, C; Riso, N; Cepeda Ribeiro, J; Moraes-Fontes, MF