Made available in DSpace on 2022-04-29T08:28:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01; Introduction: The prenatal period is highly sensitive to pharmacological interventions. The psychoactive compounds of Cannabis act directly on the endocannabinoid system, and the deleterious effects of external cannabinoids during gestation may be related to negative interference in the central nervous ...
Made available in DSpace on 2022-04-29T08:29:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Air-breathing vertebrates undergo respiratory adjustments when faced with disturbances in the gas composition of the environment. In mammals, the medullary raphe nuclei are involved in the neuronal pathway that mediates the ventilator...
Made available in DSpace on 2022-05-01T06:02:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-17; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The first third of incubation is critical for embryonic development, and environmental changes during this phase can affect the physiology and survival of the embryos. We ...
Made available in DSpace on 2022-05-01T09:47:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-08; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Amphibians may be more vulnerable to climate-driven habitat modification because of their complex life cycle dependence on land and water. Considering the current rate of ...
Made available in DSpace on 2021-06-25T12:20:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Many diseases of the respiratory system occur differently in males and females, indicating a possible role of gonadal hormones in respiratory control. We hypothesized that...
Made available in DSpace on 2021-06-25T10:50:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01; The neural network that regulates breathing shows a significant sexual dimorphism. Ovarian hormones contribute to this distinction as, in rats, ovariectomy reduces the ventilatory response to CO2. Microglia are neuroimmune cells that are sensitive to neuroendocrine changes in their environment. When rea...
Made available in DSpace on 2021-06-25T10:58:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; The pontine A5 noradrenergic group contributes to the maturation of the respiratory system before birth in rats. These neurons are connected to the neural network responsible for respiratory rhythmogenesis. In the present study, we investigated the participation of A5 noradrenergic neurons in neonates (...
Made available in DSpace on 2021-06-25T11:00:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-15; In pre-metamorphic tadpoles, the neural network generating lung ventilation is present but actively inhibited; the mechanisms leading to the onset of air breathing are not well understood. Orexin (ORX) is a hypothalamic neuropeptide that regulates several homeostatic functions, including breathing. Whil...
Made available in DSpace on 2021-06-25T11:08:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Light/dark cycle affects the physiology of vertebrates and hypothalamic orexin neurons (ORX) are involved in this function. The breathing pattern of the green iguana chang...
Made available in DSpace on 2021-06-25T10:33:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01; Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Pró-Reitoria de Pesquisa, Universidade Federal de Minas Gerais; Active expiration represents an important mechanism to improve ventilation in conditions of augmented ventilat...