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EBV and MSI status in gastric cancer: does it matter?

Nascimento, Catarina Neto do; Mascarenhas-Lemos, Luís; Silva, João Ricardo; Marques, Diogo Sousa; Gouveia, Catarina Ferreira; Faria, Ana; Velho, Sónia

We investigated the impactof microsatellite instability (MSI) and Epstein–Barr virus (EBV) status in gastric cancer (GC), regarding response to perioperative chemotherapy (POPChT), overall survival (OS), and progression-free survival (PFS). We included 137 cases of operated GC, 51 of which were submitted to POPChT. MSI status was determined by multiplex PCR and EBV status by EBV-encoded RNA in situ hybridizatio...


EBV and MSI status in gastric cancer: does it matter?

do Nascimento, Catarina Neto; Mascarenhas-Lemos, Luís; Silva, João Ricardo; Marques, Diogo Sousa; Gouveia, Catarina Ferreira; Faria, Ana; Velho, Sónia

We investigated the impactof microsatellite instability (MSI) and Epstein-Barr virus (EBV) status in gastric cancer (GC), regarding response to perioperative chemotherapy (POPChT), overall survival (OS), and progression-free survival (PFS). We included 137 cases of operated GC, 51 of which were submitted to POPChT. MSI status was determined by multiplex PCR and EBV status by EBV-encoded RNA in situ hybridizatio...


Sensitivity of the invasive bivalve Corbicula fluminea to candidate control che...

Rosa, Inês C.; Garrido, Rita; Ré, Ana; Gomes, João; Pereira, Joana L.; Gonçalves, Fernando; Costa, Raquel

The freshwater Corbicula fluminea is a major aquatic nuisance worldwide. Current pest control methods raise cost-effectiveness and environmental concerns, which motivate research into improved mitigation approaches. In this context, the susceptibility of the clams to chemicals under reduced oxygen conditions was examined. Biocides with differentmechanisms of toxicity (niclosamide, polyDADMAC, ammoniumnitrate, p...


Complicated jejuno-ileal diverticulosis

Santos, Lígia; Garrido, Rita; Sousa, Luís de

Jejuno-ileal diverticulosis is a rare and frequently asymptomatic disease. However, it can present itself with chronic manifestations (episodic abdominal pain, flatulence, diarrhea, constipation) or acute symptoms, usually associated with complications of the disease, like diverticulitis, perforation, intestinal obstruction and hemorrhage. The authors present the case of an 84 year-old woman with an acute abdom...

Date: 2008   |   Origin: Revista Portuguesa de Cirurgia

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