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Paving the way for a non‐antibiotic and microbiota friendly therapy for Helicob...

Seabra, CL; Pinho, AS; Nunes, C; Amorim, I; Pedro, N; Henriques, P; Monteiro, C; Gomes, J; Machado, C; Gartner, F; Pereira, L; Reis, S; Reis, CA

Background: The World Health Organization has identified Helicobacter pylori, a Gram-negative bacterium responsible for several gastric disorders, as one of the pathogenic bacteria that requires newer non-antibiotic approaches for its management. We previously demonstrated that nanostructured lipid carriers (NLC) loaded with docosahexaenoic acid (DHA-NLC)have excellent in vitro performance against H. pylori. Ma...


Vimentin and Ki-67 immunolabeling in canine gastric carcinomas and their progno...

Flores, AR; Rema, A; Mesquita, JR; Taulescu, M; Seixas, F; Gartner, F; Amorim, I

This study evaluated the expression of vimentin and Ki-67 proliferative index (PI) by immunohistochemistry in 30 canine gastric carcinomas (GCs) and a possible association with clinical and pathological features and patient’s survival time. Vimentin immunoreactivity was assessed in neoplastic cells (in primary lesions, emboli, and metastases) and tumor-associated stroma (TAS) of canine GCs. Ki-67 PI was quantif...


Establishment of antibody panels and histochemical techniques in routine tumor ...

Pires, MA; Gama, A; Pires, I; Seixas, F; Prada, J; Pinto, ML; Branco, S; Vala, H; Delgado, L; Faísca, P; Carvalho, I; Lima, C; Ochoa, C; Orge, L

In Portugal, Veterinary Pathology is developing rapidly, and in recent years we assist to the emergence of private laboratories and the restructuring of universities,polytechnics and public laboratories.The Portuguese Society of Animal Pathology,through its actions and its associates has been keeping the discussion among its peers in order to standardizethe criteria of description,classification and evaluation ...


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