10 documents found, page 1 of 1
Factors Associated with Acute Kidney Injury in Community-Acquired Pneumonia: De...
Teles, Carolina; Magalhães, Ana; Dias da Costa, Tiago; Barra, Cátia; Silva, Ana Luísa; Albuquerque, Fernando; Gaspar, Elsa; Santos, LèlitaIntroduction: Acute kidney injury (AKI) is a frequent complication of community-acquired pneumonia (CAP). Nonetheless, the underlying pathophysiology is not fully understood. Certain factors have shown association with increased risk, but there is still data lacking. The main objective of this study was to identify factors associated with AKI in CAP. Methods: We conducted a retrospective study in patients with ...
A Case of Atypical Pneumonia Due to Severe COVID-19 and Cross Reaction with Cox...
Reigota, Catarina Peliz; Cunha, Flávia; Lopes, Cristiana; Gaspar, ElsaN/a.; N/a.
Hemolytic Anemia in an Internal Medicine Service: Population Characterization
Brites, Luísa; Gonçalves, Mariana; Gonçalves, Tatiana; Gaspar, Elsa; Santos, Lèlita; Carvalho, ArmandoBackground: Hemolytic anemia represents 5% of all anemiasand is characterized by a reduction in the survival time ofRed Blood Cells (RBC). The destruction of RBC may resultfrom intravascular or extravascular hemolytic phenomena.The last one is most often associated with autoimmune phenomena, chemical/drug toxicity, infections, hypersplenismand mechanical destruction.The objective of the study was to describe th...
Lipoprotein (a) as a cause of statin-resistance: how to treat? – Case report
Négrier Lourenço, Carolina; Rebelo, Marta; Gaspar, Elsa; Vieira, Diniz; Silva, José Manuel; Alves de Moura, J. J.Lipoprotein (a) (Lp(a)) is considered to be a cardiovascular risk factor, and nicotinic acid is the only available drug that reduces its levels.The authors present the case of a 44-year-old male patient with hypercholesterolemia that responded poorly to statin therapy. After identifying elevated Lp(a) levels combined therapy with nicotinic acid was initiated, resulting in normalization of LDL-cholesterol levels...
Doença de deposição de cadeias leves com atingimento hepático predominante: a p...
Costa, Susana; Dias, Patrícia; Gaspar, Elsa; Cipriano, Maria Augusta; Parente, Francisco; Lourenço, Alberto; Alexandrino, Borges; Moura, J. J. Alves deA doença de depósitos de cadeias leves (DDCL) é uma das mais raras discrasias de células plasmocitárias monoclonais. Caracteriza-se pela infiltração multissistémica por cadeias leves, sendo o atingimento renal quase universal. O envolvimento hepático de forma isolada é raro, sendo este órgão geralmente afectado em doentes que também apresentam doença renal, a qual normalmente domina o quadro clínico. Os autores...
Light chain deposition disease with predominant hepatic involvement – a clinica...
Costa, Susana; Dias, Patrícia; Gaspar, Elsa; Cipriano, Maria Augusta; Parente, Francisco; Lourenço, Alberto; Alexandrino, Borges; Alves de Moura, J. J.Light chain deposition disease (LCDD) is one of the least common of the monoclonal plasma cell dyscrasias. It is characterized by multi-systemic infi ltrative light chains, with the kidney being almost always involved. Isolated liver involvement is rare and this organ is usually affected in patients who also have renal disease, dysfunction of which is the commonest clinical presentation. The authors report a pa...
Avaliação do percurso intra-hospitalar após a alta de um serviço de Medicina In...
Dias, Patrícia; Parente, Francisco; Gaspar, Elsa; Carrola, Paulo; Alexandrino, Mário; Moura, J. J. AlvesIntrodução e objectivos – O seguimento após a alta hospitalar e respectivo consumo de recursos dentro da mesma instituição poderão ser indicadores importantes na avaliação da actividade dos serviços. Com este objectivo, os autores realizaram um estudo retrospectivo analisando alguns parâmetros de avaliação após o internamento num Serviço de Medicina Interna. Material e métodos – Foram seleccionados os intername...
Assessment of the in-hospital course after discharge from an internal medicine ...
Dias, Patrícia; Parente, Francisco; Gaspar, Elsa; Carrola, Paulo; Alexandrino, Mário; Alves de Moura, J.J.Introduction and methods – Post-discharge follow-up and use of institution resources may be important indicators in the evaluation of a Services’ activity. The authors have retrospectively analyzed some post-discharge assessment parameters in an Internal Medicine Service.Material and Methods – Admissions to the Medicina II Service of the Coimbra University Hospital, who were discharged, as registered on the DRG...
The pathogenesis of atherosclerosis - Part 1
Silva, José Manuel; Devesa, Nuno; Gaspar, ElsaThe authors briefl.y describe the chronologic process of atherosclerosis and review, trying to integrate the known theories of atherogenesis, the usual evolution of the atherosclerotic plaque. ln the first part of this work only six theories are reviewed, namely the response-to-retention hypothesis, the lipid hypothesis, the monoclonal theory, the encrustation or haemostasis theory, the response-to lesion or R...
The pathogenesis of arteriosclerosis, 2ndPart
Silva, José Manuel; Monserratt Mendes, Maria; Gaspar, ElsaThe authors carry on the discussion about some of the theories concerning atherogenesis, reviewing, in this second part, the scientific evidence of the immunologic theory, the role of calcium in this process, the importance of infections, the fatigue hypothesis of Stehbens, and the role of hemodynamics. Finally the overall conclusion is that all theories contribute to atherogenesis, with more or less relative w...