2 documents found, page 1 of 1
Contribution of non-steroidal anti-inflammatory drugs to breast cancer treatmen...
Ferreira, Tiago; Faustino-Rocha, Ana I; Gaspar, VM; Medeiros, Rui; Mano, JF; Oliveira, Paula A.Chronic inflammation plays a crucial role in carcinogenesis. High levels of serum prostaglandin E2 and tissue overexpression of cyclooxygenase-2 (COX-2) have been described in breast, urinary, colorectal, prostate, and lung cancers as being involved in tumor initiation, promotion, progression, angiogenesis, and immunosuppression. Non-steroidal anti-inflammatory drugs (NSAIDs) are prescribed for several medical ...
Mammary glands of women, female dogs and female rats: similarities and differen...
Ferreira, T; Gama, A; Seixas, F; Faustino-Rocha, AI; Lopes, C; Gaspar, VM; Mano, J; Medeiros, R; Oliveira, PABreast cancer is one of the most common and well-known types of cancer among women worldwide and is the most frequent neoplasm in intact female dogs. Female dogs are considered attractive models or studying spontaneous breast cancer, whereas female rats are currently the most widely used animal models for breast cancer research in the laboratory context. Both female dogs and female rats have contributed to the ...