2 documents found, page 1 of 1
Tributyltin chloride leads to adiposity and impairs metabolic functions in the ...
Bertuloso, Bruno Duarte; Podratz, Priscila Lang; Merlo, Eduardo; Araújo, Julia Fernandez Puñal de; Lima, Leandro Ceotto FreitasTributyltin chloride (TBT) is an environmental contaminant used in antifouling paints of boats Endocrine disruptor effects of TBT are well established in animal models. However, the adverse effects on metabolism are less well understood. The toxicity of TBT in the white adipose tissue (WAT), liver and pancreas of female rats were assessed. Animals were divided into control and TBT (0.1 mg/kg/day) groups. TBT in...
Dioclea violacea lectin ameliorates oxidative stress and renal dysfunction in a...
Freitas, Flavia P. S.; Porto, Marcella L.; Tranhago, Camilla P.; Piontkowski, Rogerio; Miguel, Emilio de Castro; Miguel, Thaiz Batista Azevedo RangelAcute kidney injury (AKI) is characterized by rapid and potentially reversible decline in renal function; however, the current management for AKI is nonspecific and associated with limited supportive care. Considering the need for more novel therapeutic approaches, we believe that lectins from Dioclea violacea (Dvl), based on their antiinflammatory properties, could be beneficial for the treatment of AKI induce...