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Influence of Polymeric Blends on Bioceramics of Hydroxyapatite
Gomes, Eduardo da Silva; Lima, Antônia Millena de Oliveira; Gavinho, Sílvia Rodrigues; Graça, Manuel Pedro Fernandes; Devesa, SusanaBioceramics are used to repair, rebuild, and replace parts of the human body, e.g., bones, joints and teeth, in the form of powder, coatings or prostheses. The synthetic hydroxyapatite [Ca10(PO4)6(OH)2 (HAP)] based on calcium phosphate has been widely used in the medical and dental areas due to the chemical similarity with the inorganic component of human bone tissue. In this work, hydroxyapatite nanocrystallin...
Influence of the Particle Size on the Electrical, Magnetic and Biological Prope...
Regadas, Joana Soares; Gavinho, Sílvia Rodrigues; Teixeira, Sílvia Soreto; de Jesus, Juliana Vieira; Pádua, Ana Sofia; Silva, Jorge CarvalhoBioglasses have been used throughout the past century as a biomaterial in the bone regeneration field. However, recent studies have attempted to use them as a therapeutic material as well, mainly in the treatment of osteosarcomas. The most widely recognized bioglass is the 45S5 Bioglass, invented by Larry Hench et al., which presents higher bioactivity. A possible application of this bioglass in the treatment o...
Extensive Investigation on the Effect of Niobium Insertion on the Physical and ...
Hammami, Imen; Gavinho, Sílvia Rodrigues; Pádua, Ana Sofia; Lança, Maria do Carmo; Borges, João Paulo; Silva, Jorge Carvalho; Sá-Nogueira, IsabelDental implants have emerged as one of the most consistent and predictable treatments in the oral surgery field. However, the placement of the implant is sometimes associated with bacterial infection leading to its loss. In this work, we intend to solve this problem through the development of a biomaterial for implant coatings based on 45S5 Bioglass® modified with different amounts of niobium pentoxide (Nb2O5)....
An Eco-Friendly Process to Extract Hydroxyapatite from Sheep Bones for Regenera...
Gavinho, Sílvia Rodrigues; Bozdag, Mehmet; Kalkandelen, Cevriye; Regadas, Joana Soares; Jakka, Suresh Kumar; Gunduz, Oguzhan; Oktar, Faik NuzhetHydroxyapatite (HA) promotes excellent bone regeneration in bone-tissue engineering, due to its similarity to bone mineral and its ability to connect to living tissues. These factors promote the osteointegration process. This process can be enhanced by the presence of electrical charges, stored in the HA. Furthermore, several ions can be added to the HA structure to promote specific biological responses, such a...
Antibacterial Biomaterial Based on Bioglass Modified with Copper for Implants C...
Hammami, Imen; Gavinho, Sílvia Rodrigues; Jakka, Suresh Kumar; Valente, Manuel Almeida; Graça, Manuel Pedro Fernandes; Pádua, Ana SofiaBiofilm-related implant infections pose a substantial threat to patients, leading to inflammation in the surrounding tissue, and often resulting in implant loss and the necessity for additional surgeries. Overcoming this implantology challenge is crucial to ensure the success and durability of implants. This study shows the development of antibacterial materials for implant coatings by incorporating copper into...
Desenvolvimento de magnetolipossomas baseados em nanopartículas de ferrite de c...
Gavinho, Sílvia RodriguesAtualmente, o cancro tem-se apresentado como a doença que mais dificilmente se consegue diagnosticar pela sua atuação silenciosa e, cada vez mais, consegue arranjar estratégias para ultrapassar os tratamentos até agora desenvolvidos. Para além destes entraves, os tratamentos para combater esta doença têm sido apontados como ineficazes no que diz respeito à toxicidade e possivelmente a muitos efeitos secundários...