Encontrados 4 documentos, a visualizar página 1 de 1
p53 immunostaining pattern in Brazilian patients with hepatocellular carcinoma
Alves, Venâncio Avancini Ferreira; Nita, Marcelo Eidi; Carrilho, Flair José; Ono-nita, Suzane Kioko; Wakamatsu, Alda; Lehrbach, Dárcio MatenhauerHepatocellular carcinoma (HCC) is an important type of cancer etiologically related to some viruses, chemical carcinogens and other host or environmental factors associated to chronic liver injury in humans. The tumor suppressor gene p53 is mutated in highly variable levels (0-52%) of HCC in different countries. OBJECTIVE: The objective of the present study was to compare the frequency of aberrant immunohistoch...
Hepatobiliary alterations in massive biliary ascariasis: histopathological aspe...
Gayotto, Luiz Carlos da Costa; Muszkat, Regina Maria Leitão; Souza, Irene VieiraHepatobiliary alterations found in an autopsy case of massive Biliary Ascariasis, are reported on histological grounds. Severe cholangitis was the main finding, but other changes were also detected, such as pyloric and intestinal metaplasia, hyperplasia of the epithelial lining, with intraductal papillomas and adenomatous proliferation. Remnants of the worm were observed tightly adhered to the epithelium, formi...
An ELISA method using serum derived HDAg for the sorological detection of HDV a...
Granato, Celso; Strauss, Edna; Vitvitsky, Ludmila; Gayotto, Luiz Carlos da Costa; Trepo, ChristianOne of the main difficulties related to the detection of the Hepatitis Delta Virus (HDV) antigen and antibody has been the source of the needed HD antigen since HDV containing human and animal livers are very difficult to obtain and since yield is low. This fact prompted us to try to use the serum of patients in the acute phase of HDV infection as a source of HDAg and turn to enzyme immunoassays (EIA) instead o...
Labrea hepatitis hepatitis B and delta antigen expression in liver tissue: re...
Fonseca, José Carlos Ferraz da; Gayotto, Luiz Carlos da Costa; Ferreira, Luiz Carlos Lima; Araújo, José Ribamar; Alecrim, Wilson Duarte