2 documents found, page 1 of 1
Global impact of fixed-dose combination therapies on cardiovascular mortality a...
Watkins, David A.; Pickersgill, Sarah; Flood, David; Gaziano, Thomas A.; Huffman, Mark D.; Islam, Shofiqul; Joseph, Philip; Perel, PabloBackground: Uptake of drugs for primary and secondary prevention of cardiovascular disease is low in many countries. Single-pill combination (SPC) therapies consisting of a statin and 1 or more antihypertensive drugs, with or without aspirin, can reduce rates of fatal and nonfatal cardiovascular disease, but their use is currently limited. Objectives: The authors modeled the potential impact of widespread adopt...
The heart of the world
Di Cesare, Mariachiara; Perel, Pablo; Taylor, Sean; Kabudula, Chodziwadziwa; Bixby, Honor; Gaziano, Thomas A.; McGhie, Diana Vaca; Mwangi, JeremiahCardiovascular diseases (CVDs) are the leading cause of mortality globally. Of the 20.5 million CVD-related deaths in 2021, approximately 80% occurred in low- and middleincome countries. Using data from the Global Burden of Disease Study, NCD Risk Factor Collaboration, NCD Countdown initiative, WHO Global Health Observatory, and WHO Global Health Expenditure database, we present the burden of CVDs, associated r...