17 documents found, page 1 of 2

Asymptomatic Plasmodium vivax malaria in the Brazilian Amazon: submicroscopic p...

α-Gal immunization positively impacts Trypanosoma cruzi colonization of heart t...

Toxoplasma gondii-induced neutrophil extracellular traps amplify the innate and...

Plasmodium vivax infection alters mitochondrial metabolism in human monocytes

Improved performance of ELISA and immunochromatographic tests using a new chime...

Neutralizing antibody-independent immunity to SARS-CoV-2 in hamsters and hACE-2...

Integrative analysis of microRNA and mRNA expression profiles of monocyte-deriv...

Evaluation of three recombinant proteins for the development of ELISA and immun...

BACKGROUND Visceral Leishmaniasis (VL) is an infectious disease that is a significant cause of death among infants aged under 1 year and the elderly in Brazil. Serodiagnosis is a mainstay of VL elimination programs; however, it has significant limitations due to low accuracy. OBJECTIVE This study aimed to evaluate three recombinant Leishmania infantum proteins (rFc, rC9, and rA2) selected from previous proteomi...

Involvement of the chemokine RANTES (CCL5) in resistance to experimental infect...

The expression and putative role of chemokines during infection with Leishmania major in mice were investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.

Novel recombinant multiepitope proteins for the diagnosis of asymptomatic Leish...

Background: Visceral leishmaniasis is the most severe form of leishmaniasis. Worldwide, approximately 20% of zoonotic human visceral leishmaniasis is caused by Leishmania infantum, also known as Leishmania chagasi in Latin America. Current diagnostic methods are not accurate enough to identify Leishmania-infected animals and may compromise the effectiveness of disease control. Therefore, we aimed to produce and...