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When toxicity goes circular: Isoprostanes as markers and effectors of oxidative...

Pais, RT; Sousa, ACA; Pastorinho, MR

In normal conditions, there is a dynamic equilibrium between oxidants and antioxidants in the human body; however, when there is an unbalance in this redox state, oxidative stress occurs. In an unbalanced state, the peroxidation of polyunsaturated fatty acids originates isoprostanes (IsoPs), which can be considered as markers of oxidative stress. Since oxidative stress is associated with several non-communicabl...


Acute toxicity of plant extracts towards Daphnia magna

Ferraz, C; Pais, RT; Gaspar, C; Palmeira de Oliveira, A; Sousa, AC; Pastorinho, M. Ramiro

The demand for natural based products for the cosmetics industry is increasing sharply and therefore the search for new alternatives to the traditionally used plants is growing. These alternative plants can be an important source of bioactive compounds under a circular economy approach. Within the framework of Inovep project, several plant species, some of which autochthonous from Portugal, were identified as p...


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