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Global variation in lipoprotein/a levels among patients with coronary heart dis...

Barkas, Fotios; Brandts, Julia; De Bacquer, Dirk; Jennings, Catriona; De Backer, Guy G.; Kotseva, Kornelia; Ryden, Lars; Lip, Gregory Y. H.

Background Lipoprotein(a) [Lp(a)] is a common risk factor for atherosclerotic cardiovascular disease, potentially more atherogenic per particle than low-density lipoprotein. An estimated 1.5 billion individuals globally have elevated levels ≥125 nmol/L, considered as a risk-enhancing threshold. Although Lp(a) levels vary by ethnicity, ongoing trials of novel therapies in predominantly secondary prevention patie...


Frequency of residual combined dyslipidemia and hypertriglyceridemia in patient...

Santos, Raul D.; Ray, Kausik K.; De Bacquer, Dirk; Jennings, Catriona; Kotseva, Kornelia; Rydén, Lars; Lip, Gregory Y. H.; Erlund, Iris; Ganly, Sandra

Background and aims: Hypertriglyceridemia (HTG) is independently associated with risk of atherosclerotic events, even when LDL-cholesterol levels appear controlled. This INTERASPIRE study determined the frequency of HTG and residual combined dyslipidemia and their related factors in patients with coronary heart disease (CHD) from 13 countries across six World Health Organization (WHO) regions. Methods: Particip...


Variation in secondary prevention of coronary heart disease: the INTERASPIRE study

McEvoy, John William; Jennings, Catriona; Kotseva, Kornelia; De Bacquer, Dirk; De Backer, Guy; Erlund, Iris; Vihervaara, Terhi; Lip, Gregory Y H

Background and aims: INTERASPIRE is an international study of coronary heart disease (CHD) patients, designed to measure if guideline standards for secondary prevention and cardiac rehabilitation are being achieved in a timely manner. Methods: Between 2020 and 2023, adults hospitalized in the preceding 6-24 months with incident or recurrent CHD were sampled in 14 countries from all 6 World Health Organization r...


World Heart Federation consensus on transthyretin amyloidosis cardiomyopathy (A...

Brito, Dulce; Albrecht, Fabiano Castro; de Arenaza, Diego Perez; Bart, Nicole; Better, Nathan; Carvajal-Juarez, Isabel; Conceição, isabel; Damy, Thibaud

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive and fatal condition that requires early diagnosis, management, and specific treatment. The availability of new disease-modifying therapies has made successful treatment a reality. Transthyretin amyloid cardiomyopathy can be either age-related (wild-type form) or caused by mutations in the TTR gene (genetic, hereditary forms). It is a systemic disea...


Cardiovascular risk factors and clinical outcomes among patients hospitalized w...

Prabhakaran, Dorairaj; Singh, Kavita; Kondal, Dimple; Raspail, Lana; Mohan, Bishav; Kato, Toru; Sarrafzadegan, Nizal; Talukder, Shamim Hayder

Background and aims: Limited data exist on the cardiovascular manifestations and risk factors in people hospitalized with COVID-19 from low- and middle-income countries. This study aims to describe cardiovascular risk factors, clinical manifestations, and outcomes among patients hospitalized with COVID-19 in low, lower-middle, uppermiddle- and high-income countries (LIC, LMIC, UMIC, HIC). Methods: Through a pro...


World Heart Federation roadmap for digital health in cardiology

Tromp, Jasper; Jindal, Devraj; Redfern, Julie; Bhatt, Ami; Séverin, Tania; Banerjee, Amitava; Ge, Junbo; Itchhaporia, Dipti; Jaarsma, Tiny

More than 500 million people worldwide live with cardiovascular disease (CVD). Health systems today face fundamental challenges in delivering optimal care due to ageing populations, healthcare workforce constraints, financing, availability and affordability of CVD medicine, and service delivery. Digital health technologies can help address these challenges. They may be a tool to reach Sustainable Development Go...


Global chronic total occlusion crossing algorithm: JACC state-of-the-Art review

Wu, Eugene B.; Brilakis, Emmanouil S.; Mashayekhi, Kambis; Tsuchikane, Etsuo; Alaswad, Khaldoon; Araya, Mario; Avran, Alexandre; Azzalini, Lorenzo

The authors developed a global chronic total occlusion crossing algorithm following 10 steps: 1) dual angiography; 2) careful angiographic review focusing on proximal cap morphology, occlusion segment, distal vessel quality, and collateral circulation; 3) approaching proximal cap ambiguity using intravascular ultrasound, retrograde, and move-the-cap techniques; 4) approaching poor distal vessel quality using th...


The World Heart Federation global study on COVID-19 and cardiovascular disease

Sliwa, Karen; Singh, Kavita; Raspail, Lana; Ojji, Dike; Lam, Carolyn S.P.; Thienemann, Friedrich; Ge, Junbo; Banerjee, Amitava; Newby, L. Kristin

Background: The emergence of novel coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has presented an unprecedented global challenge for the healthcare community. The ability of SARS-CoV-2 to get transmitted during the asymptomatic phase, and its high infectivity have led to the rapid transmission of COVID-19 beyond geographic regions facilitated by...


Global chronic total occlusion crossing algorithm

Wu, Eugene B.; Brilakis, Emmanouil S.; Mashayekhi, Kambis; Tsuchikane, Etsuo; Alaswad, Khaldoon; Araya, Mario; Avran, Alexandre; Azzalini, Lorenzo

The authors developed a global chronic total occlusion crossing algorithm following 10 steps: 1) dual angiography; 2) careful angiographic review focusing on proximal cap morphology, occlusion segment, distal vessel quality, and collateral circulation; 3) approaching proximal cap ambiguity using intravascular ultrasound, retrograde, and move-the-cap techniques; 4) approaching poor distal vessel quality using th...


World Heart Federation briefing on prevention : coronavirus disease 2019 (COVID...

Thienemann, Friedrich; Pinto, Fausto J.; Grobbee, Diederick E.; Boehm, Michael; Bazargani, Nooshin; Ge, Junbo; Sliwa, Karen

In December 2019, the novel coronavirus Coronavirus Disease 2019 (COVID-19) outbreak started in Wuhan, the capital of Hubei province in China. Since then it has spread to many other regions, including low-income countries. The coronavirus was named SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2 and has spread to 78 countries (including many low-income countries), with a total of 92,818 confirmed ca...


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