18 documents found, page 1 of 2

Ocorrência de Espécies de Anopheles na área da Hidrelétrica de Balbina(AM)

Immunochemotherapy in american cutaneous leishmaniasis : immunological aspects ...

In this study, we evaluated the immune response of patients suffering from cutaneous leishmaniasis treated with two distinct protocols. One group was treated with conventional chemotherapy using pentavalent antimonium salts and the other with immunochemotherapy where a vaccine against cutaneous leishmaniasis was combined with the antimonium salt. Our results show that, although no differences were observed in t...

Vaccine for prophylaxis and immunotherapy, Brazil.

Vaccination of C57BL/10 mice against cutaneous leishmaniasis using killed proma...

Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacinand PH8 monovalent vaccine yielded the highest IFN-levels in the supernatants of spleen cell culture from vaccinated animals. Each single strain immunized group showed evidence of protective immunity six months after the challenge with promastigotes of Leishmania (Leishmania) amazonensis. No differences were d...

Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leish...

O tratamento de primeira escolha para leishmaniose tegumentar americana é o antimonial pentavalente. Embora este tratamento seja na maioria das vezes efetivo e indicado, devem ser consideradas as desvantagens tais como efeitos colaterais, longa duração do tratamento e contra-indicação para cardiopatas, nefropatas, idosos, grávidas e outras condições. Com o advento da vacina antileishmaniose tegumentar americana...

Comparison of polymerase chain reaction with other laboratory methods for the d...

An evaluation of 5 laboratory methods for diagnosing American cutaneous leishmaniasis (ACL) was carried out on patients from an endemic area of Brazil. From 164 patients presenting cutaneous lesions, and suspected to have ACL, 133 (81.1%) were confirmed for the disease by Montenegro skin test (MST) and/or parasitologic examination (PE). In both groups of patients, the positivity of polymerase chain reaction (PC...

Leishmaniose visceral canina : avaliação da metodologia sorológica utilizada em...

Foi realizado um estudo comparativo da reação de imunofluorescencia indireta em eluatos de sangue de cães infectados experimentalmente com diferentes tripanosomatideos. Utilizaram-se como antigenopromastigotas de L. mexicana, L. braziliensis e L. chagasi. Os resultados mostraram que a sensibilidade do método foi de 87,5% para o diagnostico do calazar canino, independentemente do antígeno empregado; e que ocorre...

Establishment of a microplate assay for flow cytometric assessment and it is us...

The effectiveness of flow cytometric assays for canine use is still requiring standardization. Despite several studies using purified mononuclear cells, no methodology or reference ranges are available for immunophenotyping of whole blood leukocytes (WBL). Fresh and pre-fixed WBL were used to identify cell-subsets, (Thy-1 + /CD5 + /CD4 + /CD8 + /CD21 + and CD14 + ) and measure MHC-II, CD45RA/CD45RB expression. ...

Relationship between Canine Visceral Leishmaniosis and the Leishmania (Leishman...

The skin is the first point of contact with organisms of the genus Leishmania from sand fly vectors, and apparently normal skin of sick dogs harbours amastigote forms of Leishmania chagasi. In relation to canine visceral leishmaniosis ( CVL), the ear skin was examined in 10 uninfecte d dog s ( UD s ) and in 31 dog s dog s naturally infected with L. chagasi . The infected animals consisted of 10 symptomless dogs...

Parasite density and impaired biochemical/hematological status are associated w...

We have performed a detailed investigation in 40 dogs naturally infected withLeishmania infantum ( syn. chagasi), subdivided into three groups: asymptomatic (AD = 12), oligosymptomatic (OD = 12) and symptomatic (SD = 16), based on their clinical features. Twenty non-infected dogs (CD) were included as control group. Serological analysis, performed by IFAT and ELISA, demonstrated higher antibodies titers in SD i...