3 documents found, page 1 of 1
Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile incr...
Baldeiras, Inês; Santana, Isabel; Leitão, Maria João; Gens, Helena; Pascoal, Rui; Tábuas-Pereira, Miguel; Beato-Coelho, José; Duro, DianaBackground: Cerebrospinal fluid (CSF) biomarkers have been used to increase the evidence of underlying Alzheimer’s disease (AD) pathology in mild cognitive impairment (MCI). However, CSF biomarker-based classification often results in conflicting profiles with controversial prognostic value. Normalization of the CSF Aβ42 concentration to the level of total amyloid beta (Aβ), using the Aβ42/40 ratio, has been sh...
Distrofias Musculares Progressivas — Variabilidade Clínica
Drago, Helena; Gens, Helena; Fineza, IsabelApresentam-se os resultados da análise de 38 casos com distrofia muscular progressiva seguidos na Consulta de DoençasNeuromusclares do Hospital Pediátrico de Coimbra, a partir de 1992. Os doentes com distrofia muscular de Duchenne constituem ogrupo mais representativo. Atraso motor e dificuldades da marcha foram as primeiras manifestações de doença. A idade média deaparecimento das primeiras manifestações foi 2...
Healthcare associated infection: emerging problem in a neurology department.
Palavra, Filipe; Gens, Helena; Fernandes, Carlos; Pombo, Hélia; Gonçalves, GriloHealthcare-associated infection (HAI) is, nowadays, a serious problem, contributing a lot to the burden of the hospital stays. Its impact is really huge and the study of these matters is taking a growing interest.To compare, in terms of HAI, the current Neurology Department (localized inside the building of Hospital Geral) and the oldest one, which was far away from the institutional campus. To identify difficu...