914 documents found, page 1 of 92
Ionic liquid-based nanoemulsion as a promising strategy to enhance the bioacces...
Sousa, Vítor; Lüdtke, Fernanda Luisa; Hijo, Ariel A. C. Toledo; Loureiro, Luís; Dias, Oscar; Vicente, A. A.; Pinheiro, A. C.; Geada, PedroDunaliella salina is a unicellular halophile green microalga that presents the capacity to accumulate high amounts of β-carotene, a bioactive compound widely recognized by its health benefits. To fulfil its biological functions, however, β-carotene needs to be bioaccessible, which is challenging as its bioaccessibility is typically low. A promising strategy to overcome β-carotene's low bioaccessibility is its e...
In vitro digestion and cytotoxicity study of cannabidiol-loaded nanostructured ...
Vardanega, Renata; Lüdtke, Fernanda Luisa; Loureiro, Luís; Gonçalves, Raquel F. S.; Martins, Joana T.; Pinheiro, A. C.; Vicente, A. A.Cannabidiol (CBD), a lipophilic compound with promising health benefits, such as analgesic, anti-inflammatory and neuroprotective effects, is characterized by low oral bioavailability, which limit its therapeutic application. To address these limitations, CBD was incorporated into nanostructured lipid carriers (NLCs), either as CBD-rich extract (CBDext) or as an isolate (CBDiso). The resulting systems NLC-CBDex...
Simultaneous vehiculation of curcumin and riboflavin in bigels produced through...
Clímaco, Gabrielli Nunes; Gonçalves, Raquel Filipa Silva; Fernandes, Jean Michel; Pinheiro, Ana Cristina; Vicente, A. A.; Fasolin, Luiz HenriqueThe influence of curcumin (model hydrophobic compound) and riboflavin (model hydrophilic compound) on the structure and physicochemical properties of bigels produced with cold-set whey protein isolates (WPI) was assessed. The hydrogel phase was produced with WPI (11% w/v) while for the oleogel phase, sunflower oil and glycerol monostearate (GM) (10% w/v) were used. Curcumin (0.03 mg/mL) was added to the oil pha...
Development of chitosan/navy bean extract-based nanocarriers for oral delivery ...
Oliveira Júnior, Fernando Divino; Pinheiro, A. C.; Vicente, A. A.; Cunha, Rosiane LopesStrategies have been developed for insulin administration to treat diabetes. In this sense, insulin vehiculation in nanoparticles could effectively protect this bioactive against digestion conditions and allow its intestinal absorption. To exhibit such features, it is essential to choose the materials that will compose the nanoparticles adequately. This study employed genipin-mediated crosslinking of chitosan (...
Beta-carotene-loaded Oleogels: Morphological analysis, cytotoxicity assessment,...
Martins, Artur J.; Perdigão, Lara; Gonçalves, Catarina; Amado, Isabel R.; Abreu, Cristiano S.; Vicente, A. A.; Cunha, Rosiane L.; Pastrana, Lorenzo M.Composition and structure of oleogels significantly influence their digestive behaviour, impacting triacylglycerol breakdown and the bioavailability of incorporated compounds. Texture profile analysis showed that sterol-based oleogels (STOs) exhibited 20 times higher hardness than beeswax-based oleogels (BWOs), which showed stronger cohesion due to elasticity sustained by adhesive forces. Tribological assessmen...
Estimating the biodegradation of PHB/PBAT films - An experimental design approach
Fernandes, Miguel ângelo Cavaleiro; Salvador, Andreia Filipa Ferreira; Madalena, Daniel Alexandre Silva; Vicente, A. A.The massive use of plastics in various applications, particularly packaging, generates enormous amounts of plastic waste that can be found almost everywhere, including in soil. This represents a serious environmental pollution issue since the biodegradability in soils can take several years, depending on the microbial composition, the physical and chemical characteristics of plastics, and other relevant environ...
Impact of the physiological stage on the bioaccessibility of α-tocopherol from ...
Fernandes, Jean Michel; Ménard, Olivia; Cochet, Marie-Françoise; Ossemond, Jordane; Vicente, A. A.; Pinheiro, A. C.; Dupont, DidierAge-related physiological decline negatively impacts nutrient digestion and absorption, making older adults more susceptible to diet-related diseases. Fortified and functional foods are promising strategies to enhance the delivery of nutraceuticals and bioactive compounds. However, understanding how these foods behave under age-specific gastrointestinal conditions is essential. Despite the relevance of in vitro...
The effect of conventional and ohmic heating as pasteurization methods on the m...
Aleksandrovas, Elvidas; Vasiliauskaitè, Agnè; Vieira, Jorge Miguel Magalhães; Martins, Joana T.; Pereira, Ricardo Nuno Correia; Vicente, A. A.Edible film-forming solutions typically undergo thermal treatment to ensure microbial safety before being applied to food products. The aim of this study was to assess the effects of two different heating methodsconventional heating (CH) and ohmic heating (OH)on the physical, chemical, and microbiological properties of liquid acid whey permeate (AWP) and liquid acid whey protein concentrate (AWPC) edible films....
Insights on microalgae-based technologies with potential impact on global metha...
Madureira, Leandro Filipe Feiteira; Soares, Ana Sofia Maciel; Duarte, Maria Salomé Lira; Pereira, Francisco; Francisco, DiogoThe European Unions Methane Action Plan outlined policies and targets supporting the Global Methane Pledge to cut CH4 emissions by 30% by 2030, yet urgent implementation is needed to treat medium and diluted CH4 streams. Microalgae-based technologies offer a groundbreaking solution, merging CH4 mitigation with biomass valorization to drive sustainable industrial practices. This review examines three key applica...
Development of 3D-printed foods incorporating riboflavin-loaded whey protein is...
Araújo, João Miguel Fernandes; Fernandes, Jean Michel; Madalena, Daniel Alexandre Silva; Gonçalves, Raquel Filipa Silva; Vieira, Jorge Miguel Magalhães3D printing has emerged as a groundbreaking technology, aiming to enhance sensory attributes and improving nutritional/functional aspects. Simultaneously, nano-delivery systems have emerged as an opportunity to protect bioactive compounds against degradation and improve their bioaccessibility. Therefore, a novel concept is underway, involving the 3D printing of perishable healthy foods previously fortified with...