5 documents found, page 1 of 1
Post-Infection Fatigue Syndromes in the Era of Long COVID: The Case of Myalgic ...
Sepúlveda, Nuno; Malato, João; Winck, João Carlos; Vaz Carneiro, António; Serra Hoffman, Joan; Branco, JaimeN/A; N/A
Síndromes de fadiga pós-infeção na era da COVID longa: o caso da encefalomielit...
Sepulveda, Nuno; Malato, João; Winck, João Carlos; Carneiro, António Vaz; Hoffman, Joan Serra; Branco, JaimeFaz mais de quatro anos que a Organização Mundial da Saúde (OMS) declarou o início da pandemia de COVID-19. Agora, a doença já não é considerada uma prioridade de saúde pública em Portugal. Contudo, este período de maior acalmia tem revelado um outro problema já reconhecido pelo Serviço Nacional de Saúde (SNS) e pela comunidade médica portuguesa: alguns indivíduos continuam a manifestar vários sintomas após a a...
Stability of hybrid versus vaccine immunity against BA.5 infection over 8 months
Malato, João; Ribeiro, Ruy; Fernandes, Eugénia; Leite, Pedro Pinto; Casaca, Pedro; Antunes, Carlos; Fonseca, Valter R; Gomes, MC; Graca, LuisThe coverage of SARS-CoV-2 vaccination in large parts of the world, together with the high number of breakthrough infections, especially following the emergence of Omicron subvariants, makes hybrid immunity (resulting from vaccine and infection) common. Hybrid immunity, particularly after BA.1 or BA.2 infection, confers substantial protection against the BA.5 infection. However, although the waning of protectio...
Revisiting IgG antibody reactivity to epstein-barr virus in myalgic encephalomy...
Sepúlveda, Nuno; Malato, João; Sotzny, Franziska; Grabowska, Anna D.; Fonseca, André; Cordeiro, Clara; Graça, Luís; Biecek, Przemyslaw; Behrends, UtaInfections by the Epstein-Barr virus (EBV) are often at the disease onset of patients suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). However, serological analyses of these infections remain inconclusive when comparing patients with healthy controls (HCs). In particular, it is unclear if certain EBV-derived antigens eliciting antibody responses have a biomarker potential for disease ...
The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in myalgic encep...
Malato, João; Sotzny, Franziska; Bauer, Sandra; Freitag, Helma; Fonseca, André; Grabowska, Anna D.; Graça, Luís; Cordeiro, Clara; Nacul, LuísPeople with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) often report a high frequency of viral infections and flu-like symptoms during their disease course. Given that this reporting agrees with different immunological abnormalities and altered gene expression profiles observed in the disease, we aimed at answering whether the expression of the human angiotensin-converting enzyme 2 (ACE2), the m...