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Improving health outcomes through treatment sequencing optimization in multiple...

Geraldes, C.; Neves, M.; Bergantim, R.; Silva, Catarina; Leal da Costa, F.

Objectives: Patients with multiple myeloma often require multiple treatment lines. The order in which treatments are sequenced has impact on clinical outcomes. This study aimed to estimate progression-free survival (PFS) and overall survival (OS) with common treatment sequences used in Portugal and the incremental benefit of an optimal sequence in transplant-ineligible patients with multiple myeloma. Methods: A...


The mediator role of unmet needs on quality of life in myeloma patients

Pereira, M. G.; Vilaça, M.; Pereira, M.; Ferreira, G.; Monteiro, S.; Coelho, H.; Geraldes, C.; Gonçalves, C.; da Costa, F. Leal; Marques, H.

Purpose: The diagnosis of multiple myeloma (MM) has a significant impact on patients. This study analyzed the mediating role of patients' unmet needs in the relationship between psychological morbidity/social support and quality of life (QoL). Methods: This study included 213 patients with MM recruited from the outpatient medical oncology and clinical hematology services from five hospitals. Patients who meet t...


The mediator role of unmet needs on quality of life in myeloma patients

Pereira, M. Graça; Vilaça, Margarida; Pereira, M.; Ferreira, G.; Monteiro, Luís S.; Coelho, H.; Geraldes, C.; Gonçalves, C.; da Costa, F. Leal

The diagnosis of multiple myeloma (MM) has a significant impact on patients. This study analyzed the mediating role of patients’ unmet needs in the relationship between psychological morbidity/social support and quality of life (QoL). Methods This study included 213 patients with MM recruited from the outpatient medical oncology and clinical hematology services from five hospitals. Patients who meet the study c...


Comparing spectroscopic and electrochemical properties of complexes of type Cp'...

Gonçalves, I.; Gamelas ou Carla A. Gamelas, Carla; Cabrita, C.; Hunstock, E.; Calhorda, M.; Geraldes, C.; Green, J.; Packham, E.; Drew, M.; Felix, V.


Geopolymers in cultural heritage: their application in azulejo conservation

Geraldes, C.; Lima, A.; Delgado Rodrigues, J.; Mimoso, J.; Morais Pereira, S.

Currently, the restoration materials used to fill gaps in architectural historic azulejos (e.g. lime or organic resin pastes) present relevant drawbacks in terms of compatibility, efficacy or durability. The current solutions are not able to fully protect the azulejos resulting in further deterioration. Geopolymers can be a potential solution for azulejo lacunae infill given the chemical-mineralogical similitud...


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