8 documents found, page 1 of 1
An Interactive Dashboard for Statistical Analysis of Intensive Care Unit COVID-...
Dias, Rúben; Ferreira, Artur; Pinto, Iola; Geraldes, Carlos; Von Rekowski, Cristiana; Bento, LuísBackground: COVID-19 caused a pandemic, due to its ease of transmission and high number of infections. The evolution of the pandemic and its consequences for the mortality and morbidity of populations, especially the elderly, generated several scientific studies and many research projects. Among them, we have the Predictive Models of COVID-19 Outcomes for Higher Risk Patients Towards a Precision Medicine (PREMO...
A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-...
Horta, Alexandra Bayão; Geraldes, Carlos; Salgado, Cátia; Vieira, Susana; Xavier, Miguel; Papoila, Ana LuísaIntroduction: Increased life expectancy leads to older and frailer surgical patients. Co-management between medical and surgical specialities has proven favourable in complex situations. Selection of patients for co-management is full of difficulties. The aim of this study was to develop a clinical decision support tool to select surgical patients for co-management.Material and Methods: Clinical data was collec...
Stomach cancer incidence in Southern Portugal 1998-2006: A spatio-temporal anal...
Papoila, Ana Luisa; Riebler, Andrea; Amaral-Turkman, Antónia; São João, Ricardo; Ribeiro, Conceição; Geraldes, Carlos; Miranda, AnaStomach cancer belongs to the most common malignant tumors in Portugal. Main causal factors are age, dietary habits, smoking, and Helicobacter pylori infections. As these factors do not only operate on different time dimensions, such as age, period, or birth cohort, but may also vary along space, it is of utmost interest to model temporal and spatial trends jointly. In this paper, we analyze incidence of stomac...
Stomach cancer incidence in Southern Portugal 1998-2006:a spatio-temporal analysis
Papoila, Ana Luisa; Ribeiro, Conceição; São João, Ricardo; Geraldes, Carlos; Amaral Turkman, Antónia; Miranda, AnaUnderstanding geographical differences in health, particularly in small areas, became a major concern of epidemiologists. Geographical association studies and, more recently, several spatial disease mapping studies have emerged due to the development of new spatial statistical tools. Among other diseases, these methods are being applied to analyze cancer data. However, in this kind of studies, it is of utmost i...
Colorectal cancer incidence: a spatio-temporal analysis in Southern Portugal 19...
São João, Ricardo; Papoila, Ana Luisa; Amaral Turkman, Antónia; Ribeiro, Conceição; Geraldes, Carlos; Miranda, AnaInvestigate the influence of geographical environment in colorectal cancer (CRC) incidence in Southern Portugal. Due to the important role of socioeconomic status in the risk of CRC, this variable has also been taken into account.
H5EPTPACH2OH: Synthesis, Relaxometric Characterization and 1H NMR Spectroscopic...
Torres, Susana; Martins, José A.; André, João P.; Pereira, Giovannia A.; Kiraly, Robert; Brücher, Ernö; Helm, Lothar; Tóth, Éva; Geraldes, CarlosThe synthesis and characterization of a new metal chelator, 4-(S)-hydroxymethyl-3,6,10-tri(carboxymethyl)-3,6,10-triazadodecanedioic acid (H5EPTPACH2OH), is reported. Protonation constants for the ligand H5EPTPACH2OH and for the previously reported H5EPTPAC16 have been determined by potentiometry, which reveals that both ligands display slightly higher protonation constants relative to that of the ligand DTPA5-...
Vanadium(IV and V) Complexes of Schiff Bases and Reduced Schiff Bases Derived f...
Correia, Isabel; Pessoa, João Costa; Duarte, M. Teresa; Piedade, M. Fátima Minas da; Jackush, Tamás; Kiss, Tamás; Castro, M. Margarida C. A.Several sal2en-type reduced Schiff bases have been prepared from the reaction of 2 equiv. of salicylaldehyde (or derivatives) with ethylenediamine followed by reduction with NaBH4 and subsequently characterised. The water-soluble ligands (SO3-sal)2en and R(SO3-sal)2en (SO3-sal = salicylaldehyde-5-sulphonate) have been studied by pH potentiometry and 1H NMR spectroscopy and the protonation constants of R(SO3-sal...
Competition between Li+ and Mg2+ for red blood cell membrane phospholipids: A 3...
Srinivasan, Chandra; Minadeo, Nicole; Geraldes, Carlos; Freitas, Duarte deAbstract The mode of action of the lithium ion (Li+) in the treatment of manic depression or bipolar illness is still under investigation, although this inorganic drug has been in clinical use for 50 yr. Several research reports have provided evidence for Li+/Mg2+ competition in biomolecules. We carried out this study to characterize the interactions of Li+ and Mg2+ with red blood cell (RBC) membrane components...