4 documents found, page 1 of 1
Determinants of HIV late presentation among men who have sex with men in Portug...
Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, CarmoFunding Information: The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by the European funds through grant Bio-Molecular and Epidemiological Surveillance of HIV Transmitted Drug Resistance, Hepatitis Co-Infections and Ongoing Transmission Patterns in Europe (BEST HOPE) (project funded through HIVERA: Harmonizing Integr...
Genetic modulation of anemia severity, hemolysis level, and hospitalization rat...
Germano, Isabel; Santos, Brígida; Delgadinho, Mariana; Ginete, Catarina; Lopes, Pedro; Arez, Ana Paula; Brito, Miguel; Faustino, PaulaBackground Sickle Cell Anemia (SCA) is a genetic disease caused by the c.20 A > T mutation in HBB gene, generally characterized by sickle erythrocytes, chronic hemolytic anemia, and vaso-occlusive events. This study aimed to investigate genetic modulators of anemia severity, chronic hemolytic rate, and clinical manifestations in pediatric SCA patients from Angola, where the disease is a severe public health pro...
Characterization of a large cluster of HIV-1 A1 infections detected in Portugal...
Araújo, Pedro M.M.; Carvalho, Alexandre; Pingarilho, Marta; Faria, Domitília; Pinho, Raquel; Ferreira, José; Proença, Paula; Nunes, SofiaHIV-1 subtypes associate with differences in transmission and disease progression. Thus, the existence of geographic hotspots of subtype diversity deepens the complexity of HIV-1/AIDS control. The already high subtype diversity in Portugal seems to be increasing due to infections with sub-subtype A1 virus. We performed phylogenetic analysis of 65 A1 sequences newly obtained from 14 Portuguese hospitals and 425 ...
Long-term maraviroc use as salvage therapy in HIV-2 infection
Caixas, Umbelina; Ferreira, Joana; Marinho, Aline T.; Faustino, Inês; Grilo, Nádia M.; Lampreia, Fátima; Germano, Isabel; Monteiro, E.C.; SA, Pereira