24 documents found, page 1 of 3
Sequential Use of High-Volume Plasma Exchange and Continuous Renal Replacement ...
Bragança, S; Ferraz, M; Germano, NBackground: Acute liver failure (ALF) may represent an indication for liver transplantation (LT). However, in patients who do not meet the criteria or who have contraindications for LT, support measures remain indicated since they may improve survival. Continuous renal replacement therapy (CRRT) can be considered in the presence of hyperammonemia, 3 times above the upper normal limit, and hepatic encephalopathy...
The Impact of Donor Risk Index, Recipients’ and Operative Characteristics on Po...
Cardoso, FS; Bagulho, L; Coelho, JS; Lamelas, J; Mateus, E; Mendes, M; Glória, H; Ribeiro, V; Mega, R; Pena, A; Pinto Marques, H; Germano, N; Nolasco, FBackground and Aims: The donor risk index (DRI) quantifies donor-related characteristics potentially associated with increased risk of early graft failure. We aimed to assess the impact of the DRI, recipient and perioperative factors on post liver transplant (LT) outcomes. Methods: This was a singlecenter retrospective cohort study including all adult (≥18 years) patients who underwent LT from 01/2019 to 12/201...
Fatal Case of Progressive Mpox in a Patient with AIDS—Viral Enteropathy and Mal...
Caria, J; Vara-Luiz, F; Maia, I; Joosten, A; Val-Flores, L; Pinheiro, H; Póvoas, D; Germano, N; Maltez, FWe report a fatal case of disseminated mpox infection that progressed over more than three months in an HIV-infected patient with acquired immunodeficiency syndrome (AIDS). Mucocutaneous, pleuropulmonary, central nervous system, and gastrointestinal involvement was documented. This course of disease resembles progressive vaccinia, a formerly reported disease caused by uncontrolled replication of smallpox vaccin...
Pancreatic Stone Protein As a Biomarker of Sepsis
Lopes, D; Chumbinho, B; Bandovas, JP; Faria, P; Espírito Santo, C; Ferreira, B; Val-Flores, L; Pereira, R; Germano, N; Bento, L
Autoimmunity Overlaps Primary Biliary Cirrhosis: a Not Straightforward Diagnosis
Isidoro Duarte, T; Moreira, L; Burgi Vieira, C; Germano, N
Variation in the Care of Acute Liver Failure: A Survey of Intensive Care Profes...
Cardoso, FS; Mcphail, MJ; Karvellas, CJ; Fuhrmann, V; Germano, N; Auzinger, GIntroduction: Acute liver failure (ALF) is a rare disease with potentially high mortality. We sought to assess the individual approach to ALF by intensive care unit (ICU) professionals. Methods: Cross-sectional survey of ICU professionals. Web-based survey capturing data on respondents' demographics, characteristics of patients with ALF admitted to ICU, and their management. Results: Among 204 participants from...
Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Sever...
Moreira-Rosário, A; Marques, C; Pinheiro, H; Araújo, JR; Ribeiro, P; Rocha, R; Mota, I; Pestana, D; Ribeiro, R; Pereira, A; Sousa, MJ; Pereira-Leal, JThe risk factors for coronavirus disease 2019 (COVID-19) severity are still poorly understood. Considering the pivotal role of the gut microbiota on host immune and inflammatory functions, we investigated the association between changes in the gut microbiota composition and the clinical severity of COVID-19. We conducted a multicenter cross-sectional study prospectively enrolling 115 COVID-19 patients categoriz...
High-Flow Nasal Cannula Oxygen Therapy in Pulmonary Fat Embolism - Case Report
Ferrão, J; Amaral, M; Ilharco, M; Casimiro, J; Germano, N
Acute Kidney Injury Associated with COVID-19 Infection: a Case Report
Duarte, T; Caeiro, F; Góis, M; Matos, A; Viana, H; Vieira, C; Paulos, J; Paixão, P; Matos, B; Germano, N; Nolasco, FSARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The...
Optic Nerve Sheath Diameter in Acute Liver Failure: A Prospective Cohort Study
Sousa Cardoso, F; Pereira, R; Moreno, R; Karvellas, C; Germano, NIntroduction: Acute liver failure (ALF) is a rare disease that may lead to cerebral edema and death. An increased optic nerve sheath diameter (ONSD) may reflect an early increase in intracranial pressure. We assessed the feasibility and safety of the ONSD measurement and its association with outcomes in patients with ALF. Methods: This was an open-label prospective cohort study including adult patients with ALF...