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Candida auris in Intensive Care Setting: The First Case Reported in Portugal

Henriques, João; Mixão, Verónica; Cabrita, Joana; Duarte, Tiago Isidoro; Sequeira, Tânia; Cardoso, Sofia; Germano, Nuno; Dias, Liliana; Bento, Luís

Candida auris is an opportunistic human pathogen that has rapidly spread to multiple countries and continents and has been associated with a high number of nosocomial outbreaks. Herein, we report the first case of C. auris in Portugal, which was associated with a patient transferred from Angola to an ICU in Portugal for liver transplantation after a SARS-CoV-2 infection. C. auris was isolated during the course ...


Fatal case of progressive Mpox in a patient with AIDS: viral enteropathy and ma...

Caria, João; Vara-Luiz, Francisco; Maia, Inês; Joosten, Anneke; Val-Flores, Luís; Pinheiro, Hélder; Póvoas, Diana; Germano, Nuno; Maltez, Fernando

We report a fatal case of disseminated mpox infection that progressed over more than three months in an HIV-infected patient with acquired immunodeficiency syndrome (AIDS). Mucocutaneous, pleuropulmonary, central nervous system, and gastrointestinal involvement was documented. This course of disease resembles progressive vaccinia, a formerly reported disease caused by uncontrolled replication of smallpox vaccin...


Candida auris in intensive care setting: the first case reported in Portugal

Henriques, João; Mixão, Verónica; Cabrita, Joana; Duarte, Tiago Isidoro; Sequeira, Tânia; Cardoso, Sofia; Germano, Nuno; Dias, Liliana; Bento, Luís

Candida auris is an opportunistic human pathogen that has rapidly spread to multiple countries and continents and has been associated with a high number of nosocomial outbreaks. Herein, we report the first case of C. auris in Portugal, which was associated with a patient transferred from Angola to an ICU in Portugal for liver transplantation after a SARS-CoV-2 infection. C. auris was isolated during the course ...


Acute kidney injury associated with COVID-19 infection : a case report

Duarte, Tiago; Caeiro, Fernando; Góis, Mário; Matos, António; Viana, Lena; Vieira, César; Paulos, Jorge; Paixão, Paulo; Matos, Bruno; Germano, Nuno

SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The...


Angiosarcoma of the lower limb misdiagnosed as deep thrombophlebitis – a review

Murinello, António; Fernandes, Cândida; Neta, Jorge; Árias, Jesus; Afonso, Ana; Cabral, Vitória; Germano, Nuno; Mendonça, Paula; Ribeiro, Analisa

Angiosarcomas are very rare sarcomas with vascular differentiation, high-grade malignant behaviour, early metastasis and generally bad prognosis. Early diagnosis is very important for adequate radical ablative surgery in order to obtain a better prognosis. The authors present a case of very aggressive angiosarcoma of the leg, admitted in a very advanced stage with extensive metastases, due to an initial misdiag...


Haemodynamic parameters obtained by transthoracic echocardiography and Swan-Gan...

Marcelino, Paulo; Germano, Nuno; Marum, Susan; Fernandes, Ana Paula; Ribeiro, Palmeiro; Lopes, Mário G

To compare the haemodynamic measurements of cardiac output (CO), central venous pressure (CVP), pulmonary capillary wedge pressure (Pw) and pulmonary artery systolic pressure (PASP), obtained by Swan-Ganz catheter and transthoracic echocardiography.Prospective study in a Medical/Surgical Intensive Care Unit (ICU). A total of 41 post liver transplant patients were enrolled. CO, CVP, Pw and PASP, were simultaneou...

Date: 2006   |   Origin: Acta Médica Portuguesa

Non invasive evaluation of central venous pressure using echocardiography in th...

Marcelino, Paulo; Borba, Alexandra; Fernandes, Ana Paula; Marum, Susana; Germano, Nuno; Lopes, M. Rio G.

Objectives: To determine the possibility of non-invasive estimation of central venous pressure (CVP) through inferior vena cava (IVC) analysis, using transthoracic echocardiography (TTE). Design: A prospective 3-year study. Setting: A 16-bed medical/surgical Intensive Care Unit (ICU). Methods: Patients admitted to the ICU were enrolled. CVP measurement and TTE (determining cardiac chambers dimension and left ve...


Determinantes cardíacas do tempo de ventilação mecânica e mortalidade de doente...

Marcelino, Paulo; Germano, Nuno; Nunes, Ana Paiva; Flora, Lígia; Moleiro, Ana; Marum, Susan; Fernandes, Ana Paula

Objective: To study the influence of cardiac status on the length of mechanical ventilation, outcome and disease severity in patients admitted to an Intensive Care Unit (ICU) with exacerbation of chronic respiratory failure. Design and setting: A 30-month prospective study in a 14 bed ICU Patients and methods: Fifty nine patients were enrolled, with a mean age 74.7 +/- 9.7 years, mean length of ventilator suppo...


Use of antimalarial drugs in chemoprophylaxis and treatment of patients in non ...

Germano, Nuno; Mendonça, Rogélia Paula; Murinello, António

Malaria is the most important parasitic disease of man. About 40% of world population lives in high-risk malaria endemic areas. Nowadays In Europe malaria have small expression, with a low number of clinical cases in migrant population of endemic areas and in travelers to high-risk malaria endemic areas.This article is a bibliographic review about drug interactions of the antimalarial agents used in prophylaxis...


Amiodarone pneumonitis A clinical case report

Germano, Nuno; Catarino, Maria do Carmo; Mendonça, Rogélia Paula

Amiodarone is an anti-arrhythmic drug that causes many side effects, even when used in low doses (200mg/day). The most important non-cardiologic side effect is hypersensitivity pneumonitis.We present a clinic case of a man, treated with amiodarone for one year, who was admitted with a hypersensitivity pneumonitis.The patient was treated with systemic corticosteroids and amiodarone was suspended, due to the seve...


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