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Distinct oligodendrocyte populations have spatial preference and different resp...
Floriddia, Elisa M.; Lourenço, Tânia; Zhang, Shupei; van Bruggen, David; Hilscher, Markus M.; Kukanja, Petra; Gonçalves Dos Santos, João P.Mature oligodendrocytes (MOLs) show transcriptional heterogeneity, the functional consequences of which are unclear. MOL heterogeneity might correlate with the local environment or their interactions with different neuron types. Here, we show that distinct MOL populations have spatial preference in the mammalian central nervous system (CNS). We found that MOL type 2 (MOL2) is enriched in the spinal cord when co...
Date: 2020
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Origin: Estudo Geral - Universidade de Coimbra