2 documents found, page 1 of 1
Safety, Efficacy and Pharmacokinetics of daily optimised doses of Rifampicin fo...
Espinosa-Pereiro, J; Aguiar, A; Nara, E; Medina, A; Molinas, G; Tavares, M; Tortola, T; Ghimire, S; Alfenaar, JC; Sturkenboom, MGG; Magis-Escurra, C"Background: Higher than standard doses of rifampicin could improve the treatment outcome of drug-susceptible tuberculosis without compromising the safety of patients. Methods: We performed a systematic review of prospective clinical studies including adults with pulmonary and extrapulmonary TB receiving rifampicin doses above 10mg/kg/day. We extracted the data on overall adverse events (AE), hepatic AE, sputum...
Global age-sex-specific mortality, life expectancy, and population estimates in...
Schumacher, AE; Kyu, HH; Aali, A; Abbafati, C; Abbas, J; Abbasgholizadeh, R; Abbasi, MA; Abbasian, M; Abd ElHafeez, S; Abdelmasseh, M; Abd Elsalam, SBackground: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides n...